Evidence map›Paper›PMID 32845012›Full record

ArticleEuropean journal of immunology2021

A novel method to identify Post-Aire stages of medullary thymic epithelial cell differentiation.

Pedro Ferreirinha, Camila Ribeiro, Junko Morimoto, Jonathan J M Landry, Minoru Matsumoto, Catarina Meireles, Andrea J White, Izumi Ohigashi, Leonor Araújo, Vladimir Benes and 4 more

Abstract read
In one paragraph

Article in European journal of immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Assembling the thymus medulla: Development and function of epithelial cell heterogeneity.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024
    Article
  6. Article
  7. Learning the Autoimmune Pathogenesis Through the Study of Aire.Advances in experimental medicine and biology · 2024
    Article
  8. Review
  9. Embryonic keratin19Nature communications · 2023
    Article
  10. Frontiers in immunology · 2023
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Pedro FerreirinhaInstituto de Investigação e Inovação em Saúde (I3S), Universidade do Porto, Porto, Portugal.
Camila RibeiroInstituto de Investigação e Inovação em Saúde (I3S), Universidade do Porto, Porto, Portugal.
Junko MorimotoDivision of Molecular Immunology, Institute for Enzyme Research, Tokushima University, Tokushima, Japan.
Jonathan J M LandryGenomics Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany.
Minoru MatsumotoDivision of Molecular Immunology, Institute for Enzyme Research, Tokushima University, Tokushima, Japan.
Catarina MeirelesInstituto de Investigação e Inovação em Saúde (I3S), Universidade do Porto, Porto, Portugal.
Andrea J WhiteInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, Medical School, University of Birmingham, Birmingham, UK.
Izumi OhigashiDivision of Experimental Immunology, Institute of Advanced Medical Sciences, University of Tokushima, Tokushima, Japan.
Leonor AraújoInstituto de Investigação e Inovação em Saúde (I3S), Universidade do Porto, Porto, Portugal.
Vladimir BenesGenomics Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany.
Yousuke TakahamaNational Cancer Institute, NIH, Bethesda, Maryland, USA.
Graham AndersonInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, Medical School, University of Birmingham, Birmingham, UK.ORCID 0000-0002-2917-4085
Mitsuru MatsumotoDivision of Molecular Immunology, Institute for Enzyme Research, Tokushima University, Tokushima, Japan.
Nuno L AlvesInstituto de Investigação e Inovação em Saúde (I3S), Universidade do Porto, Porto, Portugal.ORCID 0000-0002-1567-8389

Funding

Thymus biologyZIABC011806 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI TAKAHAMA, YOUSUKE · 2018 to 2025
$13.5M
FCT program "Scientific Employment Stimulus"Fundação para a Ciência e a Tecnologia, Portugal POCI-01-0145-FEDER-029129H2020 European Research Council 637843Japanese Agency for Medical Research and Development-Core Research for Evolutional Science and Technology JP16H05342Japanese Agency for Medical Research and Development-Core Research for Evolutional Science and Technology JP16H06496Japanese Agency for Medical Research and Development-Core Research for Evolutional Science and Technology JP16K21731Medical Research Council MR/T029765/1
6 · The paper itself

Abstract

Autoimmune regulator

Indexed as

AIRE ProteinAnimalsCell DifferentiationDown-RegulationEpithelial CellsGene Expression ProfilingGene Expression RegulationKeratinocytesMiceMice, Inbred C57BLThymus GlandTranscription FactorsAIRE ProteinTranscription Factorsautoimmune regulatordifferentiationmedullary thymic epithelial cellthymustolerance induction

Identifiers

PMID32845012
PMCPMC7891440

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.