Evidence map›Paper›PMID 32844743›Full record

ArticleeLife2020

Cryo-EM analysis of PIP

Yiming Niu, Xiao Tao, Kouki K Touhara, Roderick MacKinnon

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Review
  2. Molecular mechanisms of Kir channel gating.Biochemical Society transactions · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Lipid probes to study ion channels.Current opinion in chemical biology · 2025
    Review
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yiming Niu *Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, New York, United States.ORCID 0000-0002-5683-1781
Xiao Tao *Laboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, New York, United States.ORCID 0000-0002-9381-7903
Kouki K TouharaLaboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, New York, United States.ORCID 0000-0003-3167-9784
Roderick MacKinnonLaboratory of Molecular Neurobiology and Biophysics, The Rockefeller University, Howard Hughes Medical Institute, New York, United States.ORCID 0000-0001-7605-4679

Funding

Voltage-Dependent Ion Channel GatingR01GM043949 · NIGMS · ROCKEFELLER UNIVERSITY · PI MACKINNON, RODERICK · 1990 to 2024
$10.1M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM043949NIH HHS GM43949
6 · The paper itself

Abstract

G-protein-gated inward rectifier potassium (GIRK) channels are regulated by G proteins and PIP

Indexed as

G Protein-Coupled Inwardly-Rectifying Potassium ChannelsPhosphatidylinositol 4,5-DiphosphateAnimalsCryoelectron MicroscopyHumansMiceNeuronsPotassium Channels, Inwardly RectifyingProtein BindingProtein ConformationG Protein-Coupled Inwardly-Rectifying Potassium ChannelsKir2.2 channelPhosphatidylinositol 4,5-DiphosphatePotassium Channels, Inwardly RectifyingcryoEMGIRKG proteinhumanKir channelsmolecular biophysicsmousePIP2structural biology

Identifiers

PMID32844743
PMCPMC7556866

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.