Evidence map›Paper›PMID 32844458›Full record

ArticleJournal of clinical laboratory analysis2020

The predictive value of RDW in AKI and mortality in patients with traumatic brain injury.

Ruo Ran Wang, Min He, Xiao Feng Ou, Xiao Qi Xie, Yan Kang

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

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  9. Association of hyperchloremia and acute kidney injury in pediatric patients with moderate and severe traumatic brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ruo Ran WangDepartment of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Min HeDepartment of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Xiao Feng OuDepartment of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Xiao Qi XieDepartment of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Yan KangDepartment of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-5269-3863
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRed blood cell distribution width (RDW) has been validated valuable in predicting outcome and acute kidney injury (AKI) in several clinical settings. The aim of this study was to explore whether RDW is associated with outcome and AKI in patients with traumatic brain injury (TBI).

methodsPatients admitted to our hospital for TBI from January 2015 to August 2018 were included in this study. Multivariate logistic regression analysis was performed to identify risk factors of AKI and outcome in patients with TBI. The value of RDW in predicting AKI and outcome was evaluated by receiver operating characteristic (ROC) curve.

resultsThree hundred and eighteen patients were included in this study. The median of RDW was 14.25%. We divided subjects into two groups based on the median and compared difference of variables between two groups. The incidence of AKI and mortality was higher in high RDW (RDW > 14.25) group (31.45% vs 9.43%, P < .001; 69.81% vs 29.56%, P < .001). Spearman's method showed RDW was moderately associated with 90-day Glasgow Outcome Scale (GOS) (P < .001). In multivariate logistic regression analysis, RDW, lymphocyte, chlorine, and serum creatinine were risk factors of AKI. And Glasgow Coma Scale (GCS), glucose, chlorine, AKI, and RDW were risk factors of mortality. The area under the ROC curve (AUC) of RDW for predicting AKI and mortality was 0.724 (0.662-0.786) and 0.754 (0.701-0.807), respectively. Patients with higher RDW were likely to have shorter median survival time (58 vs 70, P < .001).

conclusionsRed blood cell distribution width is an independent risk factor of AKI and mortality in patients with TBI.

Indexed as

Erythrocyte IndicesAcute Kidney InjuryAdultBiomarkersBrain Injuries, TraumaticChinaFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsROC CurveBiomarkersacute kidney injurybrain traumamarkerred blood cell distribution width

Identifiers

PMID32844458
PMCPMC7521248
OpenAlexW3080588036

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.