ArticleInsights into imaging2020
Colorectal liver metastases: radiopathological correlation.
Article in Insights into imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- ESR Essentials: assessing the radiological response of liver metastases to systemic therapy-practice recommendations by the European Society of Gastrointestinal and Abdominal Radiology.European radiology · 2025Guideline
- Robust multicentre detection and classification of colorectal liver metastases on CT: application of foundation models.NPJ precision oncology · 2026Article
- Review
- A Deep Learning Algorithm for Liver Metastasis Detection at Contrast-enhanced Abdominal CT in Patients with Colorectal Cancer: A Comparative Study with Radiologists.Radiology. Imaging cancer · 2026Article
- Prospective evaluation of liver cancer volumes on non-contrast 1.5 T MR Linac imaging.Clinical and translational radiation oncology · 2026Article
- Cauliflower-Like Liver Metastases from Colon Cancer.Journal of Brown hospital medicine · 2026Article
- CRLM-GAN: a feature-constrained GAN-based deep learning framework for multi-parametric MRI-based segmentation of colorectal liver metastases before and after chemotherapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- A combination of MRI diffusion-derived vessel density (DDVD) and slow diffusion coefficient (SDC) can reliably diagnose liver hemangioma: a testing of three centers' data.Journal of gastrointestinal oncology · 2025Article
- The Evolving Application of Radiation Segmentectomy for the Treatment of Hepatic Malignancy.Radiology · 2025Review
- Preoperative imaging of colorectal liver metastases: what the radiologist and the multidisciplinary team need to know.The British journal of radiology · 2024Review
- I thought it was a hemangioma! A pictorial essay about common and uncommon liver hemangiomas' mimickers.Insights into imaging · 2024Review
- Exploring Potential Epigenetic Biomarkers for Colorectal Cancer Metastasis.International journal of molecular sciences · 2024Review
- Article
- Liver metastases: The role of magnetic resonance imaging.World journal of gastroenterology · 2023Review
- Role of stereotactic body radiotherapy in multidisciplinary management of liver metastases in patients with colorectal cancer.Japanese journal of radiology · 2022Review
- High-frame-rate contrast-enhanced ultrasound findings of liver metastasis of duodenal gastrointestinal stromal tumor: A case report and literature review.World journal of clinical cases · 2022Article
- Magnetic Resonance Features of Liver Mucinous Colorectal Metastases: What the Radiologist Should Know.Journal of clinical medicine · 2022Article
- An Analysis of Clinicopathological Outcomes and the Utility of Preoperative MRI for Patients Undergoing Resection of Mucinous and Non-Mucinous Colorectal Cancer Liver Metastases.Frontiers in oncology · 2022Article
- Imaging evaluation of the liver in oncology patients: A comparison of techniques.World journal of hepatology · 2021Review
- Identifying enhancement-based staging markers on baseline MRI in patients with colorectal cancer liver metastases undergoing intra-arterial tumor therapy.European radiology · 2021Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the development of chemotherapy regimens, targeted therapies, and hepatic surgery, the survival of patients with colorectal liver metastases (CRLM) has dramatically improved. Imaging plays a central role for the diagnosis, staging, and treatment allocation in these patients. To interpret CRLM on imaging, radiologists must be familiar with the main imaging features of untreated tumors as well as the modifications induced by systemic therapies, and their meaning in relation to pathological tumor response and tumor biology. CRLM have the same histological features as the primary tumor. Most are "non-otherwise specified" (NOS) adenocarcinomas. The mucinous tumor is the most common of the rare subtypes. In NOS tumors, imaging usually differentiates central areas of necrosis from peripheral proliferating tumors and desmoplastic reaction. Areas of mucin mixed with fibrosis are seen in mucinous subtypes to help differentiate the metastases from other tumors cysts or hemangiomas. After treatment, the viable tumor is gradually replaced by ischemic-like necrosis and fibrosis, and remnants cells are mainly located on the periphery of tumors. Imaging can help predict the degree of tumor response, but changes can be difficult to differentiate from the pretherapeutic appearance. When chemotherapy is interrupted or in case of resistance to treatment, a peripheral infiltrating halo of tumor growth may appear. The purpose of the article is to illustrate the significance of the imaging features of colorectal liver metastases during systemic therapy, using radiopathological correlations.
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