Evidence map›Paper›PMID 32844159›Full record

ReviewTherapeutic advances in reproductive health

Update on the management of poor ovarian response in IVF: the shift from Bologna criteria to the Poseidon concept.

Panagiotis Drakopoulos, Erlisa Bardhi, Liese Boudry, Alberto Vaiarelli, Antonis Makrigiannakis, Sandro C Esteves, Herman Tournaye, Christophe Blockeel

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Therapeutic advances in reproductive health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04797377 nacompletednot on this map

Effects of Autologous Intraovarian Platelet Rich Plasma in Women With Poor Ovarian Response

TypeinterventionalSponsorNadezhda Women's Health HospitalRan2021 to 2021Enrolled66ConditionsPoor Ovarian ReserveArmsAutologous ovarian PRP injection
NCT06195163 phase4not yet recruitingnot on this map

Transdermal Testosterone Pretreatment in Poor Responders With Androgen Receptor Polymorphism Undergoing ICSI: A Randomized Clinical Investigation.

TypeinterventionalSponsorInstituto BernabeuRan2025 to 2026Enrolled100ConditionsFertility DisordersArmsTransdermal Gel in Sachet Dosage Form, No pretreatment
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Panagiotis DrakopoulosCentre for Reproductive Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium. Department of Obstetrics and Gynecology, Medical School, University of Crete, Heraklion, Greece.ORCID https://orcid.org/0000-0002-9262-785X
Erlisa BardhiCenter for Reproductive Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
Liese BoudryCenter for Reproductive Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
Alberto VaiarelliG.EN.E.R.A., Centre for Reproductive Medicine, Clinica Valle Giulia, Rome, Italy.
Antonis MakrigiannakisDepartment of Obstetrics and Gynecology, Medical School, University of Crete, Heraklion, Greece.
Sandro C EstevesANDROFERT-Andrology and Human Reproduction Clinic, Brazil, São Paulo.ORCID https://orcid.org/0000-0002-1313-9680
Herman TournayeCenter for Reproductive Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
Christophe BlockeelCenter for Reproductive Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the considerate progress to which assisted reproduction technology (ART) has been subject since 1978, some issues remain unresolved. Notably, the clinical management of patients with a poor ovarian response is still a challenge in everyday practice, frustrating to both the patient and the fertility expert. Poor ovarian responders (PORs) embody 9-24% of patients undergoing ovarian stimulation, meaning that up to one in four patients conceals a poor reproductive prognosis. The last decade has witnessed the attempts of the medical community to standardize diagnosis of POR with the developing of the Bologna Criteria and the subsequent evolution of the low prognosis patient elaborated in the POSEIDON classification. The aim of this article is to summarize all evidence concerning etiology and management of poor ovarian response, including the most recent advances and future prospects in this regard.

Indexed as

Bologna criteriaIVFpoor ovarian responder (POR)poor ovarian responsePoseidon classification

Identifiers

PMID32844159
PMCPMC7416136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.