ArticleTH open : companion journal to thrombosis and haemostasis2020
COVID-19 and Cold Agglutinin Hemolytic Anemia.
Article in TH open : companion journal to thrombosis and haemostasis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The JANUS of chronic inflammatory and autoimmune diseases onset during COVID-19 - A systematic review of the literature.Journal of autoimmunity · 2021Pooled it
- Autoimmune and Rheumatic Manifestations Associated With COVID-19 in Adults: An Updated Systematic Review.Frontiers in immunologyPooled it
- COVID-19-Associated Cold Agglutinin Syndrome and Hemophagocytosis in a Patient with Monoclonal Gammopathy of Undetermined Significance.Mediterranean journal of hematology and infectious diseases · 2025Article
- Coexistence of Cold Agglutinin and Cryoglobulin in a Patient With Severe Anemia Following COVID-19 Infection.Cureus · 2024Article
- Understanding autoimmune response after SARS-CoV-2 infection and the pathogenesis/mechanisms of long COVID.Medical review (2021) · 2024Review
- Cold Agglutinin Disease and COVID-19: A Scoping Review of Treatments and Outcomes.Journal of clinical medicine research · 2024Article
- Hemolytic anemia in COVID-19.Annals of hematology · 2022Review
- Severe Anemia Due to Cold Agglutinin Syndrome in a COVID-19 Patient with IgM Monoclonal Gammopathy of Undetermined Significance Successfully Treated with Corticosteroids.Internal medicine (Tokyo, Japan) · 2022Article
- The striking mimics between COVID-19 and malaria: A review.Frontiers in immunology · 2022Review
- Article
- Anti-SARS-CoV-2 and anti-cytokine storm neutralizing antibody therapies against COVID-19: Update, challenges, and perspectives.International immunopharmacology · 2021Review
- Adaptive Immunity and the Risk of Autoreactivity in COVID-19.International journal of molecular sciences · 2021Review
- Cold agglutinin disease and COVID-19 requiring therapeutic plasma exchange.BMJ case reports · 2021Article
- COVID-19 and autoimmune diseases.Current opinion in rheumatology · 2021Review
- Infectious Complications in Autoimmune Hemolytic Anemia.Journal of clinical medicine · 2021Review
- Complement Mediated Hemolytic Anemias in the COVID-19 Era: Case Series and Review of the Literature.Frontiers in immunology · 2021Review
- Cold agglutinin associated with COVID-19 infection in a thalassemia patient with multiple alloantibodies: A case of cold hemagglutinin disease (CAD) with complex antibody detection.Hematology, transfusion and cell therapyArticle
- Are Patients With Autoimmune Cytopenias at Higher Risk of COVID-19 Pneumonia? The Experience of a Reference Center in Northern Italy and Review of the Literature.Frontiers in immunologyReview
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Novel coronavirus disease 2019 (COVID-19) has spread throughout the world and has infected close to 4 million people. It commonly presents with fever, cough, and fatigue. Due to the high inflammatory response, it is suggested that the coagulation cascade is enhanced causing thrombotic events for many patients. We describe a patient with clinical features of cerebrovascular accident, as well as documented blood clots in bilateral upper extremities. Labs revealed the presence of cold agglutinin hemolytic anemia. The association between cold agglutinin autoimmune hemolytic anemia and thrombotic events in COVID-19 patients has not been well investigated. The patient unfortunately passed away within 48 hours after admission. This case stresses the importance of considering a full workup to diagnose autoimmune hemolytic anemia (AIHA) in COVID-19 patients with thromboses and possible implications for management.
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Registered trials
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