ArticleHeliyon2020
Leptin levels in SARS-CoV-2 infection related respiratory failure: A cross-sectional study and a pathophysiological framework on the role of fat tissue.
Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 4 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Investigating the shared genetic architecture between COVID-19 and obesity: a large-scale genome wide cross-trait analysis.Frontiers in endocrinology · 2024Pooled it
- Organokines in COVID-19: A Systematic Review.Cells · 2023Pooled it
- A meta-analysis of the association between obesity and COVID-19.Epidemiology and infection · 2020Pooled it
- On the whereabouts of SARS-CoV-2 in the human body: A systematic review.PLoS pathogens · 2020Pooled it
- Trial
- Observational
- Observational
- Assessment of muscle wasting in intensive care unit patients with and without COVID-19 using ultrasound imaging and bioimpedance analysis.BMC anesthesiology · 2026Article
- Diagnostic and immunological roles of leptin gene rs7799039 polymorphism and cytokines in COVID-19, HCV, and dual infection.Scientific reports · 2026Article
- Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates.PLoS pathogens · 2025Article
- Correlation between blood cell indices and adiponectin and leptin levels in COVID-19.Biomolecules & biomedicine · 2025Article
- Changes in Circulating Adipokine Levels in COVID-19 Patients.Journal of clinical medicine · 2024Article
- New-onset diabetes in children during the COVID-19 Pandemic: an assessment of biomarkers and psychosocial risk factors at play in Mississippi.Annals of pediatric endocrinology & metabolism · 2024Article
- Dynamic changes of hematological and hemostatic parameters in COVID-19 hospitalized patients: Potential role as severity biomarkers for the Chilean population.Journal of medical biochemistry · 2024Article
- Are adipokines related to COVID-19 and its severity? A systematic review and meta-analysis.Medicine and pharmacy reports · 2024Review
- Diabetes Mellitus, Energy Metabolism, and COVID-19.Endocrine reviews · 2024Review
- Outcomes of the combined lifestyle intervention CooL during COVID-19: a descriptive case series study.BMC public health · 2024Article
- Macrophage Activation Syndrome in Coinciding Pandemics of Obesity and COVID-19: Worse than Bad.Advances in experimental medicine and biology · 2024Review
- Identification of distinct phenotypes and improving prognosis using metabolic biomarkers in COVID-19 patients.Critical care science · 2024Article
- Influence of obesity on mortality, mechanical ventilation time and mobility of critical patients with COVID-19.Critical care science · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is a risk factor for SARS-CoV-2 infected patients to develop respiratory failure. Leptin produced in visceral fat might play a role in the deterioration to mechanical ventilation. A cross sectional study was performed. The mean BMI was 31 kg/m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.