ReviewWorld journal of transplantation2020
Current protocols and outcomes of ABO-incompatible kidney transplantation.
Review in World journal of transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Midterm Outcome of AB0 Incompatible Kidney Transplantation in Children and Adolescents-A Single Center Experience.Pediatric transplantation · 2026Article
- A retrospective cohort study of infective complications and graft outcomes over 5 years in ABO-incompatible kidney transplant recipients: experience from a tertiary care centre in Saudi Arabia.Annals of medicine and surgery (2012) · 2026Article
- Immunoadsorption as a Rescue Therapy for Very High Anti-B Titer in ABO-Incompatible Kidney Transplantation.The American journal of case reports · 2025Article
- Steroid Use in ABO-Incompatible Kidney Transplants: Withdrawal vs Maintenance.Annals of transplantation · 2025Article
- Comparison of domino transplantation with Two-Way Paired Exchange and normal transplantation: acute rejection, surgical complications, and 5-year survival outcomes.Langenbeck's archives of surgery · 2025Article
- Recent Advances across the Spectrum of Heart Failure and Heart Transplant.Journal of clinical medicine · 2024Article
- Addressing Kidney Transplant Shortage: The Potential of Kidney Paired Exchanges in Jordan.Journal of transplantation · 2024Review
- Safety and Feasibility of Immunoadsorption with Heparin Anticoagulation in Preparation of ABO-Incompatible Kidney Transplantation: A Retrospective Single-Center Study.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023Article
- Enzymatic blood group conversion of human kidneys during ex vivo normothermic machine perfusion.The British journal of surgery · 2023Article
- Circulating Permeability Factors in Focal Segmental Glomerulosclerosis:Kidney international reports · 2022Article
- Case Report: Successful ABO-Incompatible Deceased Donor Kidney Transplantation in an Infant Without Pre-transplant Immunological Treatment.Frontiers in medicine · 2022Article
- Antibody-mediated rejection in xenotransplantation: Can it be prevented or reversed?XenotransplantationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the principal obstacles in transplantation from living donors is that approximately 30% are immunologically incompatible because of the presence in the recipient of antibodies directed against the human leukocyte antigen system of the donor or because of the incompatibility of the ABO system. The aim of this review is to describe the more recent data from the literature on the different protocols used and the clinical outcomes of ABO-incompatible kidney transplantation. Two different strategies are used to overcome these barriers: desensitization of the recipient to remove the antibodies and to prevent their rebound after transplantation and the exchange of organs between two or more pairs. The largest part of this review is dedicated to describing the techniques of desensitization. Even if the first reports of successful renal transplantation between ABO-incompatible pairs have been published by 1980, the number of ABO-incompatible transplants increased substantially in this century because of our improved knowledge of the immune system and the availability of new drugs. Rituximab has substantially replaced splenectomy. The technique of apheresis has improved and more recently a tailored desensitization proved to be the more efficient strategy avoiding an excess of immunosuppression with the related side effects. Recent reports document outcomes for such transplantation similar to the outcomes of standard transplantation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.