ArticleNature communications2020
Reduced serial dependence suggests deficits in synaptic potentiation in anti-NMDAR encephalitis and schizophrenia.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
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Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- Serial dependence in visual perception: A meta-analysis and review.Journal of vision · 2023Pooled it
- Convergent multidimensional neural phenotypes in human patients and schizophrenia-relevant mouse models identify reduced recurrent excitation in cortical circuits.medRxiv : the preprint server for health sciences · 2026Article
- Anti-NMDAR encephalitis impairs intrinsic hippocampal dynamics through neuronal hypercoupling, hub dominance, and aberrant ensembles.Molecular psychiatry · 2026Article
- Article
- Redundant prefrontal hemispheres adapt storage strategy to working memory demands.Nature communications · 2026Article
- Predictive Inference Alterations in Psychosis Proneness Show Task-Dependent Signatures.Annals of the New York Academy of Sciences · 2026Article
- Antibody-Mediated Mechanisms in Autoimmune Neurological Disorders.The European journal of neuroscience · 2026Review
- Preserved contextual modulation of eye movements in psychosis prone individuals.Journal of vision · 2026Article
- Prior Trial Effects on Working Memory in Schizophrenia, Bipolar Disorder, and Healthy Control Individuals.JAMA psychiatry · 2026Article
- Article
- D-serine ameliorates cognitive deficits by preserving neuronal and synaptic function in experimental anti-NMDAR encephalitis.Journal of neuroinflammation · 2026Article
- Large-scale mega-analysis indicates that serial dependence deteriorates perceptual decision-making.Nature human behaviour · 2026Article
- Is repulsive serial bias in visual perception driven by adaptation mechanisms?Journal of vision · 2026Article
- Attractive and repulsive history effects in categorical and continuous estimates of orientation perception.Journal of vision · 2025Article
- Bistable Perception Discriminates Between Depressive Patients, Controls, Schizophrenia Patients, and Their Siblings.Schizophrenia bulletin · 2025Article
- Reduced weighting of short-term perceptual priors during auditory perceptual decision-making in psychosis-prone individuals.BMC biology · 2025Article
- Autoimmune neuropsychiatric disorders manifesting with psychosis.The Journal of clinical investigation · 2025Review
- Between repulsion and attraction in serial biases: Replication of Chen and Bae (2024).Journal of vision · 2025Article
- N-methyl-d-aspartate receptor hypofunction causes recurrent and transient failures of perceptual inference.Brain : a journal of neurology · 2025Article
- Intact Serial Dependence in Schizophrenia: Evidence from an Orientation Adjustment Task.Schizophrenia bulletin · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A mechanistic understanding of core cognitive processes, such as working memory, is crucial to addressing psychiatric symptoms in brain disorders. We propose a combined psychophysical and biophysical account of two symptomatologically related diseases, both linked to hypofunctional NMDARs: schizophrenia and autoimmune anti-NMDAR encephalitis. We first quantified shared working memory alterations in a delayed-response task. In both patient groups, we report a markedly reduced influence of previous stimuli on working memory contents, despite preserved memory precision. We then simulated this finding with NMDAR-dependent synaptic alterations in a microcircuit model of prefrontal cortex. Changes in cortical excitation destabilized within-trial memory maintenance and could not account for disrupted serial dependence in working memory. Rather, a quantitative fit between data and simulations supports alterations of an NMDAR-dependent memory mechanism operating on longer timescales, such as short-term potentiation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.