ArticleNature communications2020
Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis.
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In one paragraph
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 2% of its field
What it found
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Who cites it
87 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.
- The calcium-sensing receptor in sepsis and septic shock, mechanistic pathways and translational perspectives: a systematic review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Pooled it
- Trained immunity in chronic, relapsing and low-grade joint inflammation.Nature reviews. Rheumatology · 2026Review
- [Immune cell populations in rheumatoid arthritis and giant cell arteritis].Zeitschrift fur Rheumatologie · 2026Review
- NLRP3 inflammasome promotes PAD2/PAD4 release and protein citrullination in rheumatoid arthritis.Communications biology · 2026Article
- Infectious bronchitis virus accessory protein 3a induces renal inflammatory injury by activating the NLRP3 inflammasome via ER calcium mobilization and mitochondrial ROS production.Journal of virology · 2026Article
- Article
- Long-Term Static Cultivation Alters Lipid Metabolism and Bioenergetic Capacity in A549 Cells.International journal of molecular sciences · 2026Article
- Deficiency of lysosomal TMEM175 in myeloid macrophages exerts anti-tumor immunity via inflammasome and cross-presentation pathway.Nature communications · 2026Article
- Single-Cell Sequencing Reveals Circadian Sensitivity of Noise-Induced Hearing Loss Mediated by Macrophage-Driven NLRP3 Inflammasome Activation.Neuroscience bulletin · 2026Article
- Calcimimetics and CaSR signaling in CKD-MBD: bone-immune-vascular crosstalk and therapeutic potential.Frontiers in immunology · 2026Review
- Functionalized hydrocaffeic acid-chitosan/EGTA hydrogel rescues mitochondrial dysfunction for immunomodulation and joint repair in rheumatoid arthritis.Materials today. Bio · 2025Article
- Mechanisms of NLRP3 inflammasome in chronic kidney disease and the effects of traditional Chinese medicines.Renal failure · 2025Review
- Molecular mechanisms and regulation of inflammasome activation and signaling: sensing of pathogens and damage molecular patterns.Cellular & molecular immunology · 2025Review
- Salt-Induced Vascular Damage in Hypertension Involves Redox Activation of PARP/TRPM2 Signaling and Inflammasome Assembly.American journal of hypertension · 2025Article
- NLRP3 Inflammasome-Mediated Pyroptosis in Osteoporosis: Osteoimmune Mechanisms and Therapeutic Targeting.Journal of cellular and molecular medicine · 2025Review
- Cardiac alterations induced by Trypanosoma cruzi extracellular vesicles and immune complexes.PLoS neglected tropical diseases · 2025Article
- Unraveling the causal nexus of cathepsins and rheumatoid arthritis: Insights from a two-sample Mendelian randomization framework.Medicine · 2025Article
- The Multifaceted Role of Calcium Signaling in Regulated Necrosis.Biomolecules · 2025Review
- The formation and function of calciprotein particles.Pflugers Archiv : European journal of physiology · 2025Review
- An Overview of Hexavalent Chromium-Induced Necroptosis, Pyroptosis, and Ferroptosis.Biological trace element research · 2025Review
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 4 institutions in 2 countries.
Elisabeth Jäger *Department of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.ORCID http://orcid.org/0000-0001-7342-3459
Supriya Murthy *Department of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.ORCID http://orcid.org/0000-0001-8934-0842
Caroline SchmidtDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.ORCID http://orcid.org/0000-0002-7717-7272
Magdalena HahnDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.ORCID http://orcid.org/0000-0002-3195-6123
Sarah StrobelDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.
Anna PetersRudolf Schönheimer Institute of Biochemistry, Faculty of Medicine, Leipzig University, Johannisallee 30, 04103, Leipzig, Germany.ORCID http://orcid.org/0000-0002-7914-9275
Claudia StäubertRudolf Schönheimer Institute of Biochemistry, Faculty of Medicine, Leipzig University, Johannisallee 30, 04103, Leipzig, Germany.ORCID http://orcid.org/0000-0003-0721-8507
Pelin SungurJena Center for Soft Matter (JCSM), Friedrich-Schiller-University Jena, Humboldtstraße 10, 07743, Jena, Germany.ORCID http://orcid.org/0000-0003-3414-5331
Tom VenusInstitute for Medical Physics and Biophysics, Leipzig University, Härtelstraße 16-18, 04107, Leipzig, Germany.
Mandy GeislerInstitute of Bioanalytical Chemistry, Center for Biotechnology and Biomedicine, Leipzig University, Deutscher Platz 5, 04103, Leipzig, Germany.
Veselina RadushevaDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.
Stefanie RapsDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.
Kathrin RotheDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.
Roger ScholzDepartment of Orthopaedic, Trauma and Plastic Surgery, Leipzig University, Liebigstraße 20, Leipzig, Germany.
Sebastian JungDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.
Sylke WagnerDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.
Matthias PiererDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.
Olga SeifertDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.
Wenhan ChangUCSF Department of Veterans Affairs Medical Center, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-6583-7176
Irina Estrela-LopisInstitute for Medical Physics and Biophysics, Leipzig University, Härtelstraße 16-18, 04107, Leipzig, Germany.
Nora RaulienDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany.
Knut KrohnDNA Core Unit Leipzig, Liebigstraße 19, 04103, Leipzig, Germany.ORCID http://orcid.org/0000-0001-8110-1273
Norbert SträterInstitute of Bioanalytical Chemistry, Center for Biotechnology and Biomedicine, Leipzig University, Deutscher Platz 5, 04103, Leipzig, Germany.
Stephanie HoeppenerJena Center for Soft Matter (JCSM), Friedrich-Schiller-University Jena, Humboldtstraße 10, 07743, Jena, Germany.ORCID http://orcid.org/0000-0002-5770-5197
Torsten SchönebergRudolf Schönheimer Institute of Biochemistry, Faculty of Medicine, Leipzig University, Johannisallee 30, 04103, Leipzig, Germany.
Manuela RossolDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany. manuela.rossol@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0002-6946-8520
Ulf WagnerDepartment of Internal Medicine, Division of Rheumatology, Leipzig University, Liebigstraße 19, 04103, Leipzig, Germany. ulf.wagner@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0002-8106-4924
Leipzig University · DEFriedrich Schiller University Jena · DEUniversity Hospital Leipzig · DESan Francisco VA Medical Center · US
Funding
UCSF Core Center for Musculoskeletal Biology and MedicineP30AR066262 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA · 2014 to 2018
$3.0MRegulation of Parathyroid Functions By G-Protein Coupled ReceptorsR01DK122259 · NIDDK · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI CHANG, WENHAN, VILARDAGA, JEAN-PIERRE · 2019 to 2023
$2.2MRegulation of PTH secretion by TRPC1R01DK121656 · NIDDK · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI CHANG, WENHAN, TSIOKAS, LEONIDAS · 2019 to 2022
$2.1MA novel treatment for bone fracture repairI01BX003453 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI CHANG, WENHAN · 2018 to 2021
–BLRD Research Career Scientist Award ApplicationIK6BX004835 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI Wenhan Chang · 2020 to 2026
–BLRD VA I01 BX003453BLRD VA IK6 BX004835NIAMS NIH HHS P30 AR066262NIDDK NIH HHS R01 DK121656NIDDK NIH HHS R01 DK122259
Abstract
Increased extracellular Ca
Indexed as
alpha-2-HS-GlycoproteinAnimalsArthritis, RheumatoidCalcinosisCalciumCells, CulturedHumansInflammasomesInflammationInterleukin-1betaMiceMonocytesNLR Family, Pyrin Domain-Containing 3 ProteinPhosphatesPinocytosisReceptors, Calcium-Sensingalpha-2-HS-GlycoproteinCalciumInflammasomesInterleukin-1betaNLR Family, Pyrin Domain-Containing 3 ProteinPhosphatesReceptors, Calcium-Sensing
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.