Evidence map›Paper›PMID 32843538›Full record

ArticlemSystems2020

Benchmarking Bacterial Promoter Prediction Tools: Potentialities and Limitations.

Murilo Henrique Anzolini Cassiano, Rafael Silva-Rocha

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Article
  3. TheMicroorganisms · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Deep Generative Model-Driven Design of Microbial Synthetic Promoters.Journal of microbiology and biotechnology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Genomic features and fitness cost of co-existence ofFrontiers in cellular and infection microbiology · 2025
    Article
  14. Predicting Promoters in Multiple Prokaryotes with Prompt.Interdisciplinary sciences, computational life sciences · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Classification of Promoter Sequences from Human Genome.International journal of molecular sciences · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Murilo Henrique Anzolini CassianoFMRP - University of São Paulo, Ribeirão Preto, SP, Brazil.
Rafael Silva-RochaFMRP - University of São Paulo, Ribeirão Preto, SP, Brazil silvarochar@usp.br.ORCID 0000-0001-6319-631X
Universidade de Ribeirão Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The promoter region is a key element required for the production of RNA in bacteria. While new high-throughput technology allows massively parallel mapping of promoter elements, we still mainly rely on bioinformatics tools to predict such elements in bacterial genomes. Additionally, despite many different prediction tools having become popular to identify bacterial promoters, no systematic comparison of such tools has been performed. Here, we performed a systematic comparison between several widely used promoter prediction tools (BPROM, bTSSfinder, BacPP, CNNProm, IBBP, Virtual Footprint, iPro70-FMWin, 70ProPred, iPromoter-2L, and MULTiPly) using well-defined sequence data sets and standardized metrics to determine how well those tools performed related to each other. For this, we used data sets of experimentally validated promoters from

Indexed as

bacterial promotersbioinformaticscis-regulatory elementspromoter prediction

Identifiers

PMID32843538
PMCPMC7449607
OpenAlexW3081166989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.