Evidence map›Paper›PMID 32843367›Full record

ArticleRNA (New York, N.Y.)2020

In vitro studies provide insight into effects of Dicer-2 helicase mutations in

Helen M Donelick, Loïc Talide, Matthieu Bellet, P Joseph Aruscavage, Emilie Lauret, Eric R G R Aguiar, Joao T Marques, Carine Meignin, Brenda L Bass

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Biochemical and structural basis of Dicer helicase function unveiled by resurrecting ancient proteins.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  3. The PAZ domain ofRNA (New York, N.Y.) · 2025
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  4. Article
  5. Article
  6. Review
  7. eLife · 2024
    Article
  8. Article
  9. bioRxiv : the preprint server for biology · 2024
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Phagocytosis Is the Sole Arm ofFrontiers in immunology · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Helen M Donelick *Department of Biochemistry, University of Utah, Salt Lake City, Utah 84112, USA.ORCID 0000-0001-8562-2260
Loïc Talide *Université de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, 67084 Strasbourg, France.
Matthieu BelletUniversité de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, 67084 Strasbourg, France.
P Joseph AruscavageDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112, USA.
Emilie LauretUniversité de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, 67084 Strasbourg, France.
Eric R G R AguiarCentro de Biotecnologia e Genética, Universidade Estadual de Santa Cruz, Ilhéus 45662-900, Bahia, Brazil.ORCID 0000-0002-8143-5756
Joao T MarquesUniversité de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, 67084 Strasbourg, France.ORCID 0000-0002-3457-3320
Carine MeigninUniversité de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, 67084 Strasbourg, France.ORCID 0000-0002-6588-9045
Brenda L BassDepartment of Biochemistry, University of Utah, Salt Lake City, Utah 84112, USA.ORCID 0000-0003-1728-2254
Centre National de la Recherche Scientifique · FRUniversity of Utah · USUniversidade Estadual de Santa Cruz · BRUniversidade Federal de Minas Gerais · BR

Funding

Mechanistic insights into Dicer, a double-stranded RNA processing enzymeR01GM121706 · NIGMS · UNIVERSITY OF UTAH · PI BASS, BRENDA L. · 2017 to 2020
$1.5M
Program for Interdisciplinary Training in CHemical BiologyT32GM122740 · NIGMS · UNIVERSITY OF UTAH · PI KAY, MICHAEL S · 2018 to 2022
$932k
NIGMS NIH HHS R01 GM121706NIGMS NIH HHS T32 GM122740
6 · The paper itself

Abstract

In vitro,

Indexed as

MutationAdenosine TriphosphateAnimalsDNA HelicasesDrosophila melanogasterDrosophila ProteinsFemaleIn Vitro TechniquesMaleMicroRNAsRibonuclease IIIRNA, Double-StrandedRNA HelicasesRNA, Small InterferingAdenosine TriphosphateDCR-2 protein, DrosophilaDNA HelicasesDrosophila ProteinsMicroRNAsRibonuclease IIIRNA, Double-StrandedRNA HelicasesRNA, Small InterferingantiviraldsRNAinnate immunityRNAi

Identifiers

PMID32843367
PMCPMC7668257
OpenAlexW3080515891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.