Observational studySurgery2020
The continuum of complications in survivors of necrotizing pancreatitis.
Observational study in Surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 53 citations in OpenAlex.
- Modulation of Pancreatic Activity by Ghrelin and Its Potential Effects on Acute Pancreatitis.Digestive diseases and sciences · 2026Review
- Management of walled-off pancreatic necrosis (WON) beyond the conventional step-up strategy: a retrospective cohort study.Surgical endoscopy · 2026Article
- Splanchnic venous thrombosis in necrotizing pancreatitis: recanalization and the effectiveness of anticoagulant therapy.World journal of emergency surgery : WJES · 2026Article
- Interpretable XGBoost-SHAP model predicts short-term recurrence after first-episode acute pancreatitis.Journal of family medicine and primary care · 2026Article
- Multi-detector computed tomography imaging of inflammatory colonic strictures in recurrent acute pancreatitis: a case description and literature analysis.Quantitative imaging in medicine and surgery · 2025Article
- Acute Pancreatitis-Associated Thrombotic Venopathy.Cureus · 2025Article
- Influencing factor analysis and clinical efficacy of early intervention in severe acute pancreatitis with persistent organ failure.Scientific reports · 2025Observational
- Incidence and Management of Splanchnic Vein Thrombosis in Pancreatic Diseases.United European gastroenterology journal · 2025Review
- Article
- Co-Existing Non-Occlusive Splenic Vein and Superior Mesenteric Vein Thrombosis in an Acute Necrotic Pancreatitis Patient-A Case Report.Clinical case reports · 2024Article
- Article
- Exploring the gut microbiota's crucial role in acute pancreatitis and the novel therapeutic potential of derived extracellular vesicles.Frontiers in pharmacology · 2024Review
- Transgastric pancreatic necrosectomy: Tricks of the trade.Surgery open science · 2023Article
- Acute pancreatitis: Structured report template of magnetic resonance imaging.World journal of radiology · 2023Review
- Gastrointestinal Fistulas in Necrotizing Pancreatitis Receiving a Step-Up Approach Incidence, Risk Factors, Outcomes and Treatment.Journal of inflammation research · 2023Article
- Pancreatitis associated anxiety, depression, and stress: Hypothesis, definition, and intervention.Surgery open science · 2022Article
- Early prediction of acute necrotizing pancreatitis by artificial intelligence: a prospective cohort-analysis of 2387 cases.Scientific reports · 2022Article
- The role of endoscopic therapy in the minimally invasive management of pancreatic necrosis.The Korean journal of internal medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundNecrotizing pancreatitis survivors develop complications beyond infected necrosis that often require invasive intervention. Remarkably few data have cataloged these late complications after acute necrotizing pancreatitis resolution. We sought to identify the types and incidence of complications after necrotizing pancreatitis.
designAn observational study was performed evaluating 647 patients with necrotizing pancreatitis captured in a single-institution database between 2005 and 2017 at a tertiary care hospital. Retrospective review and analysis of newly diagnosed conditions attributable to necrotizing pancreatitis was performed. Exclusion criteria included the following: death before disease resolution (n = 57, 9%) and patients lost to follow-up (n = 12, 2%).
resultsA total of 578 patients were followed for a median of 46 months (range, 8 months to 15 y) after necrotizing pancreatitis. In 489 (85%) patients 1 or more complications developed and included symptomatic disconnected pancreatic duct syndrome (285 of 578, 49%), splanchnic vein thrombosis (257 of 572, 45%), new endocrine insufficiency (195 of 549, 35%), new exocrine insufficiency (108 of 571, 19%), symptomatic chronic pancreatitis (93 of 571, 16%), incisional hernia (89 of 420, 21%), biliary stricture (90 of 576, 16%), chronic pain (44 of 575, 8%), gastrointestinal fistula (44 of 578, 8%), pancreatic duct stricture (30 of 578, 5%), and duodenal stricture (28 of 578, 5%). During the follow-up period, a total of 340 (59%) patients required an invasive intervention after necrotizing pancreatitis resolution. Invasive pancreatobiliary intervention was required in 230 (40%) patients.
conclusionLate complications are common in necrotizing pancreatitis survivors. A broad variety of problems manifest themselves after resolution of the acute disease process and often require invasive intervention. Necrotizing pancreatitis patients should be followed lifelong by experienced clinicians.
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