ArticleRespiratory medicine
Association of low FVC spirometric pattern with WTC occupational exposures.
Article in Respiratory medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03295279 (Pulmonary Diseases in WTC Workers), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pulmonary Diseases in WTC Workers: Symptoms, Function, and Chest CT Correlates
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Impact of War on Asthma, a Systematic Review and Meta-Analysis: An EAACI Task Force Report.Allergy · 2026Pooled it
- Assessing the impact of World Trade Center (WTC) exposures on post-bronchodilator lung function: Insights from WTC survivor population.PloS one · 2026Article
- Spirometric pattern transitions in a World Trade Center occupational cohort on longitudinal surveillance.Respiratory medicine · 2025Article
- On the association of chemical pollutant exposures and disordered sleep outcomes.Sleep medicine reviews · 2023Article
- Article
- Exposure to World Trade Center Dust Exacerbates Cognitive Impairment and Evokes a Central and Peripheral Pro-Inflammatory Transcriptional Profile in an Animal Model of Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2023Article
- World Trade Center Health Program best practices for diagnosing and treating chronic obstructive pulmonary disease.Archives of environmental & occupational health · 2023Article
- Reduced forced vital capacity is independently associated with, aging, height and a poor socioeconomic status: a report from the Tunisian population-based BOLD study.BMC pulmonary medicine · 2022Article
- Review
- Asthma-COPD overlap in World Trade Center Health Registry enrollees, 2015-2016.The Journal of asthma : official journal of the Association for the Care of Asthma · 2021Article
- Association of quantitative CT lung density measurements and lung function decline in World Trade Center workers.The clinical respiratory journal · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundA reduced forced vital capacity without obstruction (low FVC) is the predominant spirometric abnormality reported in workers and volunteers exposed to dust, gases, and fumes at the World Trade Center (WTC) disaster site in 2001-2002. While low FVC has been associated with obesity and metabolic syndrome, its association with WTC occupational exposures has not been demonstrated. We estimated the prevalence of this abnormality and examined its association with WTC exposure level.
methodsLongitudinal study of the relation between arrival at the WTC site within 48 h and FVC below the lower limit of normal (FVC < LLN, with normal FEV
resultsThe prevalence of low FVC increased from 17.0% (95% CI 15.4%, 18.5%) in June 2003, to 26.4% (95% CI 24.8%, 28.1%) in June 2018, and exceeded at both times that of obstruction. The rate of FVC decline was -43.7 ml/year during the study period. In a multivariable analysis adjusting for obesity, metabolic syndrome indicators, and other factors, early arrival at the WTC disaster site was significantly associated with low FVC, but only among men (OR
conclusionsAmong WTC workers, the prevalence of low FVC increased over a 16-year period. Early arrival to the WTC disaster site was significantly associated with low FVC in males.
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