Evidence map›Paper›PMID 32843013›Full record

ArticleBMC complementary medicine and therapies2020

Starch composition, glycemic indices, antioxidant properties and carbohydrate hydrolyzing enzymes activities of African star apple fruit parts.

Olubunmi B Ajayi, Folake L Oyetayo, Seun F Akomolafe

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 30 citations in OpenAlex.

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  5. Effect ofJournal of diabetes and metabolic disorders · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Olubunmi B AjayiDepartment of Biochemistry, Ekiti State University, Ado Ekiti, Ekiti State, P.M.B. 5363, Nigeria.
Folake L OyetayoDepartment of Biochemistry, Ekiti State University, Ado Ekiti, Ekiti State, P.M.B. 5363, Nigeria.
Seun F AkomolafeDepartment of Biochemistry, Ekiti State University, Ado Ekiti, Ekiti State, P.M.B. 5363, Nigeria. purposefulseun@yahoo.co.uk.ORCID http://orcid.org/0000-0002-7061-8303
Ekiti State University · NG

Funding

TETFund Institutional Based Research, Ekiti State University, Ado Ekiti, Nigeria. Tetfund 2016/2017 Intervention year
6 · The paper itself

Abstract

backgroundAfrican star apple (Chrysophyllum albidum) is a traditonal fruit, which is predominant in tropical regions with the fruit parts consumed by the populace and used in folklore to manage diabetes. However, the likely activity mechanism is still undetermined. The current study examined and compared the inhibitory abilities of African star apple fruit parts on selected key enzymes related to diabetes mellitus in the pancreas tissue of rat.

methodsInhibitory effect of aqueous extract (1:10 w/v) of African star apple fruit parts (pulp, cotyledon, seed coat and pulp coat) on the activities of α-amylase, α-glucosidase, as well as their starch composition, phenolic constituents, estimated glycemic index, and antioxidant properties were assessed.

resultsThe fruit parts showed low sugar, eGI, amylose, and amylopectin contents. The analysis also showed that the fruit parts inhibited α-glucosidase and α-amylase activities and exhibited antioxidant properties. Furthermore, the fruit parts contain high concentrations of beta-amyrin acetate, eleagine, epicatechin, epigallocatechin, skatole, stigmasterol and tetrahydro - 2- methylharman as revealed by HPLC-DAD.

conclusionThe fruit part low estimated glycemic indices, strong antioxidant properties, inhibition of α-amylase and α-glucosidase activities exhibited might be related to the bioactive compounds contained in the extract. This could also be a potential mechanism for the use in the prevention and management of type-2 diabetes. Nevertheless, the African star apple pulp coat displayed the highest property in comparison to other parts of the fruit.

Indexed as

Africaalpha-Amylasesalpha-GlucosidasesAnimalsAntioxidantsDiabetes Mellitus, ExperimentalDisease Models, AnimalFruitGlycemic IndexMalePancreasPlant ExtractsRatsRats, WistarSapotaceaeStarchalpha-Amylasesalpha-GlucosidasesAntioxidantsPlant ExtractsStarchAcarboseAfrican star apple fruitAntioxidantDiabetes mellitusα-Amylaseα-Glucosidase

Identifiers

PMID32843013
PMCPMC7446214
OpenAlexW3081354152

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.