Evidence map›Paper›PMID 32842722›Full record

Trial reportKorean journal of anesthesiology2020

The relative analgesic value of a femoral nerve block versus adductor canal block following total knee arthroplasty: a randomized, controlled, double-blinded study.

Jeff C Gadsden, Siddharth Sata, W Michael Bullock, Amanda H Kumar, Stuart A Grant, Joshua R Dooley

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Korean journal of anesthesiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07629388 (Comparative Study Assessing the Efficacy of a Combined Distal Femoral Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07629388 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Comparative Study Assessing the Efficacy of a Combined Distal Femoral Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty (TKA)

TypeinterventionalSponsorGCS Ramsay Santé pour l'Enseignement et la RechercheRan2026 to 2027Enrolled240ConditionsPain After Total Knee Arthroplasty, Pain ManagementArmsCombined distal femoral nerve block, Saphenous nerve block alone, Standard perioperative care in both groups
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. [Comparison of the effects of sciatic nerve block combined with continuted femoral nerve block or continuted adductor canal block on pain and motor function after total knee arthroplasty].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024
    Trial
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  7. Ambulatory total hip and knee arthroplasty: a literature review and perioperative considerations.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jeff C GadsdenDepartment of Anesthesiology, Duke University Medical Center, Duke University, Durham, NC, USA.
Siddharth SataDepartment of Anesthesiology, Duke University Medical Center, Duke University, Durham, NC, USA.
W Michael BullockDepartment of Anesthesiology, Duke University Medical Center, Duke University, Durham, NC, USA.
Amanda H KumarDepartment of Anesthesiology, Duke University Medical Center, Duke University, Durham, NC, USA.
Stuart A GrantDepartment of Anesthesiology, Duke University Medical Center, Duke University, Durham, NC, USA.
Joshua R DooleyDepartment of Anesthesiology, University of North Carolina Medical Center, University of North Carolina, Chapel Hill, NC, USA.
Duke Medical Center · USUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple comparative studies report that adductor canal blocks provide similar pain relief to femoral nerve blocks following total knee arthroplasty. However, adductor canal blockade fails to anesthetize several important femoral nerve branches that contribute to knee innervation. We sought to clarify this anatomic discrepancy by performing both blocks in sequence, using patients as their own controls. We hypothesized that patients would experience additional pain relief following a superimposed femoral nerve block, demonstrating that these techniques are not equivalent.

methodsSixteen patients received continuous adductor canal block before undergoing knee arthroplasty under general anesthesia. In the recovery room, patients reported their pain score on a numeric scale of 0-10. Once a patient reached a score of five or greater, he/she was randomized to receive an additional femoral nerve block using 2% chloroprocaine or saline sham, and pain scores recorded every 5 min for 30 min. Patients received opioid rescue as needed. Anesthesiologists performing and assessing block efficacy were blinded to group allocation.

resultsPatients randomized to chloroprocaine versus saline reported significantly improved median pain scores 30 min after the femoral block (2.0 vs. 5.5, P = 0.0001). Patients receiving chloroprocaine also required significantly fewer morphine equivalents during the 30 min post-femoral block (1.0 vs. 4.5 mg, P = 0.03).

conclusionsAdductor canal block is a useful technique for postoperative pain following total knee arthroplasty, but it does not provide equivalent analgesic efficacy to femoral nerve block. Future studies comparing efficacy between various block sites along the thigh are warranted.

Indexed as

AgedAnalgesiaAnesthetics, LocalArthroplasty, Replacement, KneeAutonomic Nerve BlockDouble-Blind MethodFemaleFemoral NerveHumansMaleMiddle AgedPain MeasurementPostoperative PainProcaineProspective StudiesThighAnesthetics, LocalchloroprocaineProcaineAcute painAdductor canal blockFemoral nerve blockRopivacaineTotal knee arthroplastyUltrasound

Identifiers

PMID32842722
PMCPMC7533174
OpenAlexW3080544574

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.