Evidence map›Paper›PMID 32842664›Full record

ReviewInternational journal of molecular sciences2020

Insights into the Role of Bioactive Food Ingredients and the Microbiome in Idiopathic Pulmonary Fibrosis.

Josep Mercader-Barceló, Joan Truyols-Vives, Carlos Río, Nora López-Safont, Ernest Sala-Llinàs, Alice Chaplin

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

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  17. Protective effect ofBioscience of microbiota, food and health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Josep Mercader-BarcelóInflammation, Repair and Cancer in Respiratory Diseases Research Group, Balearic Islands Health Research Institute (IdISBa), Ctra. Valldemossa 79, 07120 Palma, Balearic Islands, Spain.ORCID 0000-0002-5293-2809
Joan Truyols-VivesDepartment of Fundamental Biology and Health Sciences, University of the Balearic Islands (UIB), 07122 Palma, Balearic Islands, Spain.
Carlos RíoInflammation, Repair and Cancer in Respiratory Diseases Research Group, Balearic Islands Health Research Institute (IdISBa), Ctra. Valldemossa 79, 07120 Palma, Balearic Islands, Spain.
Nora López-SafontADEMA School University, University of the Balearic Islands (UIB), 07009 Palma, Balearic Islands, Spain.ORCID 0000-0002-5452-7794
Ernest Sala-LlinàsInflammation, Repair and Cancer in Respiratory Diseases Research Group, Balearic Islands Health Research Institute (IdISBa), Ctra. Valldemossa 79, 07120 Palma, Balearic Islands, Spain.
Alice ChaplinLipids in Human Pathology Research Group, Balearic Islands Health Research Institute (IdISBa), Ctra. Valldemossa 79, 07120 Palma, Balearic Islands, Spain.ORCID 0000-0003-0685-4237
Health Research Institute of the Balearic Islands · ESUniversitat de les Illes Balears · ESCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic disease mainly associated with aging and, to date, its causes are still largely unknown. It has been shown that dietary habits can accelerate or delay the occurrence of aging-related diseases; however, their potential role in IPF development has been underestimated so far. The present review summarizes the evidence regarding the relationship between diet and IPF in humans, and in animal models of pulmonary fibrosis, in which we discuss the bioactivity of specific dietary food ingredients, including fatty acids, peptides, amino acids, carbohydrates, vitamins, minerals and phytochemicals. Interestingly, many animal studies reveal preventive and therapeutic effects of particular compounds. Furthermore, it has been recently suggested that the lung and gut microbiota could be involved in IPF, a relationship which may be linked to changes in immunological and inflammatory factors. Thus, all the evidence so far puts forward the idea that the gut-lung axis could be modulated by dietary factors, which in turn have an influence on IPF development. Overall, the data reviewed here support the notion of identifying food ingredients with potential benefits in IPF, with the ultimate aim of designing nutritional approaches as an adjuvant therapeutic strategy.

Indexed as

Food IngredientsAgingAmino AcidsAnimalsAvitaminosisDietary Fats, UnsaturatedGastrointestinal MicrobiomeHumansIdiopathic Pulmonary FibrosisLungMicrobiotaMicronutrientsPhytochemicalsVitaminsAmino AcidsDietary Fats, UnsaturatedFood IngredientsMicronutrientsPhytochemicalsVitaminsdietgut-lung axisidiopathic pulmonary fibrosismicrobiota

Identifiers

PMID32842664
PMCPMC7503951
OpenAlexW3080891546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.