Evidence map›Paper›PMID 32842636›Full record

ArticleViruses2020

Employing Molecular Phylodynamic Methods to Identify and Forecast HIV Transmission Clusters in Public Health Settings: A Qualitative Study.

Shannan N Rich, Veronica L Richards, Carla N Mavian, William M Switzer, Brittany Rife Magalis, Karalee Poschman, Shana Geary, Steven E Broadway, Spencer B Bennett, Jason Blanton and 7 more

Abstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shannan N RichDepartment of Epidemiology, College of Public Health and Health Professions & College of Medicine, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-1203-2443
Veronica L RichardsDepartment of Epidemiology, College of Public Health and Health Professions & College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Carla N MavianEmerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
William M SwitzerDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30322, USA.ORCID 0000-0003-4591-8731
Brittany Rife MagalisEmerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
Karalee PoschmanDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30322, USA.
Shana GearyDivision of Public Health, Injury and Violence Prevention Branch, North Carolina Department of Health and Human Services, Raleigh, NC 27699, USA.
Steven E BroadwayFlorida Department of Health, Division of Disease Control and Health Protection, Bureau of Communicable Diseases, HIV/AIDS Section, Tallahassee, FL 32399, USA.
Spencer B BennettFlorida Department of Health, Bureau of Public Health Laboratories, Jacksonville, FL 32202, USA.
Jason BlantonFlorida Department of Health, Bureau of Public Health Laboratories, Jacksonville, FL 32202, USA.ORCID 0000-0002-2002-7281
Thomas LeitnerTheoretical Biology & Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
J Lucas BoatwrightDepartment of Plant and Environmental Sciences, Clemson University, Clemson, SC 29634, USA.ORCID 0000-0003-4371-2457
Nichole E StettenDepartment of Epidemiology, College of Public Health and Health Professions & College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Robert L CookDepartment of Epidemiology, College of Public Health and Health Professions & College of Medicine, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-7770-3754
Emma C SpencerFlorida Department of Health, Division of Disease Control and Health Protection, Bureau of Communicable Diseases, HIV/AIDS Section, Tallahassee, FL 32399, USA.
Marco SalemiEmerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
Mattia ProsperiDepartment of Epidemiology, College of Public Health and Health Professions & College of Medicine, University of Florida, Gainesville, FL 32610, USA.

Funding

Reconstructing HIV Epidemics from HIV PhylogeneticsR01AI087520 · NIAID · TRIAD NATIONAL SECURITY, LLC · PI Thomas K. Leitner · 2010 to 2026
$11.2M
Leveraging public health genotyping databases for near real-time HIV surveillanceR01AI135946 · NIAID · TRIAD NATIONAL SECURITY, LLC · PI LEITNER, THOMAS K. · 2019 to 2023
$4.2M
Forecasting trajectories of HIV transmission networks with a novel phylodynamic and deep learning frameworkR01AI145552 · NIAID · UNIVERSITY OF FLORIDA · PI Simone Marini, Mattia Prosperi · 2020 to 2026
$3.6M
Translational Science Training to Reduce the Impact of Alcohol on HIV InfectionT32AA025877 · NIAAA · UNIVERSITY OF FLORIDA · PI Robert L Cook, DEBRA E LYON · 2018 to 2026
$3.3M
HIV Dynamic Modelling for Identification of Transmission Epicenters (HIV-DYNAMITE)R21AI138815 · NIAID · UNIVERSITY OF FLORIDA · PI PROSPERI, MATTIA, SALEMI, MARCO · 2018 to 2019
$419k
NIAAA NIH HHS T32-AA025877NIAID NIH HHS R01 AI087520NIAID NIH HHS R01 AI135946NIAID NIH HHS R01 AI145552NIAID NIH HHS R21 AI138815
6 · The paper itself

Abstract

Molecular HIV surveillance is a promising public health strategy for curbing the HIV epidemic. Clustering technologies used by health departments to date are limited in their ability to infer/forecast cluster growth trajectories. Resolution of the spatiotemporal dynamics of clusters, through phylodynamic and phylogeographic modelling, is one potential strategy to develop a forecasting tool; however, the projected utility of this approach needs assessment. Prior to incorporating novel phylodynamic-based molecular surveillance tools, we sought to identify possible issues related to their feasibility, acceptability, interpretation, and utility. Qualitative data were collected via focus groups among field experts (

Indexed as

Cluster AnalysisFemaleFocus GroupsForecastingHIV-1HIV InfectionsHumansMaleMolecular EpidemiologyPhylogeographyPublic HealthQualitative Researchfocus groupsHIV phylogeneticsHIV preventionmolecular epidemiologyqualitative researchsurveillance

Identifiers

PMID32842636
PMCPMC7551766

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.