Evidence map›Paper›PMID 32842589›Full record

ArticleLife (Basel, Switzerland)2020

Impact of Mitochondrial DNA Mutations on Carotid Intima-Media Thickness in the Novosibirsk Region.

Tatiana V Kirichenko, Anastasia I Ryzhkova, Vasily V Sinyov, Marina D Sazonova, Varvara A Orekhova, Vasily P Karagodin, Elena V Gerasimova, Mikhail I Voevoda, Alexander N Orekhov, Yulia I Ragino and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Mitochondria: From Physiology to Pathology.Life (Basel, Switzerland) · 2021
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Tatiana V KirichenkoLaboratory of Cellular and Molecular Pathology of Cardiovascular System, Research Institute of Human Morphology, 3 Tsyurupy Str., 117418 Moscow, Russia.ORCID 0000-0002-2899-9202
Anastasia I RyzhkovaLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 8 Baltiyskaya Str., 125315 Moscow, Russia.
Vasily V SinyovLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 8 Baltiyskaya Str., 125315 Moscow, Russia.
Marina D SazonovaLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 8 Baltiyskaya Str., 125315 Moscow, Russia.
Varvara A OrekhovaLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 8 Baltiyskaya Str., 125315 Moscow, Russia.
Vasily P KaragodinLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 8 Baltiyskaya Str., 125315 Moscow, Russia.
Elena V GerasimovaV.A.Nasonova Research Institute of Rheumatology, 34A Kashirskoe sh., 115522 Moscow, Russia.ORCID 0000-0001-5815-561X
Mikhail I VoevodaResearch Institute of Internal and Preventive Medicine-Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, 630089 Novosibirsk, Russia.ORCID 0000-0001-9425-413X
Alexander N OrekhovLaboratory of Cellular and Molecular Pathology of Cardiovascular System, Research Institute of Human Morphology, 3 Tsyurupy Str., 117418 Moscow, Russia.ORCID 0000-0002-3318-4681
Yulia I RaginoResearch Institute of Internal and Preventive Medicine-Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, 630089 Novosibirsk, Russia.ORCID 0000-0002-4936-8362
Igor A SobeninLaboratory of Cellular and Molecular Pathology of Cardiovascular System, Research Institute of Human Morphology, 3 Tsyurupy Str., 117418 Moscow, Russia.ORCID 0000-0003-0978-6444
Margarita A SazonovaLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 8 Baltiyskaya Str., 125315 Moscow, Russia.ORCID 0000-0002-8610-4593
Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RUInstitute of Cytology and Genetics · RUAssociation of Rheumatologists of Russia · RUPlekhanov Russian University of Economics · RUResearch Institute of Human Morphology · RU

Funding

Russian Science Foundation 20-15-00364
6 · The paper itself

Abstract

The search for markers of predisposition to atherosclerosis development is very important for early identification of individuals with a high risk of cardiovascular disease. The aim of the present study was to investigate the association of mitochondrial DNA mutations with carotid intima-media thickness and to determine the impact of mitochondrial heteroplasmy measurements in the prognosis of atherosclerosis development. This cross-sectional, population-based study was conducted in 468 subjects from the Novosibirsk region. It was shown that the mean (carotid intima-media thickness) cIMT correlated with the following mtDNA mutations: m.15059G>A (

Indexed as

atherosclerosiscardiovascular risk factorscarotid intima-media thicknessmitochondrial mutations

Identifiers

PMID32842589
PMCPMC7554768
OpenAlexW3081036506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.