Evidence map›Paper›PMID 32842556›Full record

ArticleMarine drugs2020

Preparation and Neuroprotective Activity of Glucuronomannan Oligosaccharides in an MPTP-Induced Parkinson's Model.

Yingjuan Liu, Weihua Jin, Zhenzhen Deng, Jing Wang, Quanbin Zhang

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Neuroprotective Effects of Oligosaccharides FromFrontiers in pharmacology · 2022
    Article
  6. Glucuronomannan GM2 fromMarine drugs · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yingjuan LiuKey Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Weihua JinCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.
Zhenzhen DengKey Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Jing WangKey Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Quanbin ZhangKey Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Chinese Academy of Sciences · CNZhejiang University of Technology · CN

Funding

China Postdoctoral Science Foundation NO. 2018M640611National Key R&D Plan of China No. 2018YFD0901104Shandong Provincial Natural Science Foundation NO. ZR2019BD026Zhejiang Provincial Natural Science Foundation of China No. LY19D060006
6 · The paper itself

Abstract

Parkinson's disease (PD), characterized by dopaminergic neuron degeneration in the substantia nigra and dopamine depletion in the striatum, affects up to 1% of the global population over 50 years of age. Our previous study found that a heteropolysaccharide from Saccharina

Indexed as

Seaweed1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineAnimalsAntiparkinson AgentsApoptosisApoptosis Regulatory ProteinsBehavior, AnimalBrainDisease Models, AnimalDopaminergic NeuronsGlucuronatesMaleMannoseMice, Inbred C57BLMotor ActivityOligosaccharides1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineAntiparkinson AgentsApoptosis Regulatory ProteinsGlucuronatesglucuronomannanMannoseOligosaccharidesTyrosine 3-Monooxygenaseapoptosisbehavioral deficitsglucuronomannan oligosaccharidesParkinson’ disease

Identifiers

PMID32842556
PMCPMC7551172
OpenAlexW3080430253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.