Evidence map›Paper›PMID 32841704›Full record

SynthesisThe Journal of hospital infection2020

Microwave- and heat-based decontamination of N95 filtering facepiece respirators: a systematic review.

S Gertsman, A Agarwal, K O'Hearn, R Webster, A Tsampalieros, N Barrowman, M Sampson, L Sikora, E Staykov, R Ng and 5 more

Abstract readSystematic Review
In one paragraph

Synthesis in The Journal of hospital infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Research on Dry Microwave Heating Infectious Aerosols or Droplets on Respirators.IEEE transactions on microwave theory and techniques · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Increased plastic pollution due to COVID-19 pandemic: Challenges and recommendations.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2021
    Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

S GertsmanCHEO Research Institute, Ottawa, Ontario, Canada.
A AgarwalMax Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
K O'HearnCHEO Research Institute, Ottawa, Ontario, Canada.
R WebsterClinical Research Unit, CHEO, Ottawa, Ontario, Canada.
A TsampalierosClinical Research Unit, CHEO, Ottawa, Ontario, Canada.
N BarrowmanClinical Research Unit, CHEO, Ottawa, Ontario, Canada.
M SampsonLibrary Services, CHEO, Ottawa, Ontario, Canada.
L SikoraHealth Sciences Library, University of Ottawa, Ottawa, Ontario, Canada.
E StaykovDepartment of Biology, University of Ottawa, Ottawa, Ontario, Canada.
R NgCHEO Research Institute, Ottawa, Ontario, Canada.
J GibsonCHEO Research Institute, Ottawa, Ontario, Canada.
T DinhMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
K AgyeiDepartment of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.
G ChamberlainDepartment of Pediatrics, CHEO, Ottawa, Ontario, Canada.
J D McNallyCHEO Research Institute, Ottawa, Ontario, Canada; Department of Pediatrics, CHEO, Ottawa, Ontario, Canada. Electronic address: dmcnally@cheo.on.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn pandemics such as COVID-19, shortages of personal protective equipment are common. One solution may be to decontaminate equipment such as facemasks for reuse.

aimTo collect and synthesize existing information on decontamination of N95 filtering facepiece respirators (FFRs) using microwave and heat-based treatments, with special attention to impacts on mask function (aerosol penetration, airflow resistance), fit, and physical traits.

methodsA systematic review (PROSPERO CRD42020177036) of literature available from Medline, Embase, Global Health, and other sources was conducted. Records were screened independently by two reviewers, and data was extracted from studies that reported on effects of microwave- or heat-based decontamination on N95 FFR performance, fit, physical traits, and/or reductions in microbial load.

findingsThirteen studies were included that used dry/moist microwave irradiation, heat, or autoclaving. All treatment types reduced pathogen load by a log

conclusionsMicrowave irradiation and heat may be safe and effective viral decontamination options for N95 FFR reuse during critical shortages. The evidence does not support autoclaving or high-heat (>90°C) approaches. Physical degradation may be an issue for certain mask models, and more real-world evidence on fit is needed.

Indexed as

Guidelines as TopicHot TemperatureUltraviolet RaysCoronavirus InfectionsDecontaminationEquipment ReuseHumansRespiratory Protective DevicesCOVID-19DecontaminationFiltering facepiece respiratorN95PandemicPersonal protective equipment

Identifiers

PMID32841704
PMCPMC7443086

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.