Evidence map›Paper›PMID 32841658›Full record

ArticleJournal of molecular biology2020

Structure and Reconstitution of an MCU-EMRE Mitochondrial Ca

Chongyuan Wang, Rozbeh Baradaran, Stephen Barstow Long

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Mitochondrial CaCommunications biology · 2026
    Article
  2. Article
  3. Article
  4. Mitochondrial CaJournal of cellular physiology · 2025
    Review
  5. TMEM65 functions as the mitochondrial NaNature cell biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Nanodiscs: A toolkit for membrane protein science.Protein science : a publication of the Protein Society · 2021
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chongyuan WangStructural Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Rozbeh BaradaranStructural Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
Stephen Barstow LongStructural Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. Electronic address: Longs@mskcc.org.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Mechanisms of Ion Channels in Calcium SignalingR35GM131921 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Stephen Barstow Long · 2019 to 2026
$7.4M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R35 GM131921
6 · The paper itself

Abstract

The proteins MCU and EMRE form the minimal functional unit of the mitochondrial calcium uniporter complex in metazoans, a highly selective and tightly controlled Ca

Indexed as

AnimalsCalciumCalcium-Binding ProteinsCalcium ChannelsCation Transport ProteinsHumansMitochondriaMitochondrial MembranesMitochondrial Membrane Transport ProteinsModels, MolecularProtein ConformationProtein DomainsCalciumCalcium-Binding ProteinsCalcium ChannelsCation Transport Proteinsmitochondrial calcium uniporterMitochondrial Membrane Transport Proteinscalcium channelflux assayion channelmembrane proteinreconstitution

Identifiers

PMID32841658
PMCPMC7577567
OpenAlexW3081231770

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.