ArticlePediatric pulmonology2020
Risk factors for atopic diseases and recurrent respiratory tract infections in children.
Article in Pediatric pulmonology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 45 citations in OpenAlex.
- Trial
- Early-Life Nutrition: The Interplay of Nutritional, Microbial, Genetic, and Environmental Factors in Food Allergy Development and Prevention.Nutrients · 2026Review
- Magnitude of atopic dermatitis and associated factors among children in northwest Ethiopia.Scientific reports · 2025Article
- Prevalence of food and inhalant allergies in infants and children from the Nanhai area of Foshan city.BMC pediatrics · 2025Article
- Article
- Prevalence, severity, and risk factors of eczema among young children and adolescents in Saudi Arabia: A national cross-sectional study, 2019.The journal of allergy and clinical immunology. Global · 2024Article
- Differences in the prevalence of allergy and asthma among US children and adolescents during and before the COVID-19 pandemic.BMC public health · 2024Article
- Article
- Antibody deficiencies in children are associated with prematurity and a family history of infections.Pediatric research · 2023Article
- Prevalence, severity, and risk factors of allergic rhinitis among schoolchildren in Saudi Arabia: A national cross-sectional study, 2019.The World Allergy Organization journal · 2023Article
- Association of low physical activity with higher respiratory tract infections frequency among pre-school children.Pediatric research · 2023Article
- Atopic Dermatitis: Disease Features, Therapeutic Options, and a Multidisciplinary Approach.Life (Basel, Switzerland) · 2023Review
- Duration of Neonatal Antibiotic Exposure in Preterm Infants in Association with Health and Developmental Outcomes in Early Childhood.Antibiotics (Basel, Switzerland) · 2023Article
- Allergen Sensitization in Children in Weifang, China: Differences Between Monosensitization and Polysensitization.Journal of asthma and allergy · 2023Article
- Influence factors for upper respiratory tract infection in Chinese rural children: A cross-sectional study.Frontiers in pediatrics · 2022Article
- Turbinate Hypertrophy, Allergic Rhinitis, and Otitis Media.Current allergy and asthma reports · 2021Review
- Asthma, Allergic Rhinitis, and Atopic Dermatitis Incidence in Korean Adolescents before and after COVID-19.Journal of clinical medicine · 2021Article
- Review
- Risk factors for atopic diseases and recurrent respiratory tract infections in children.Pediatric pulmonology · 2020Article
- Finding a molecular genetic marker for the incidence of recurrent episodes of acute obstructive bronchitis in children.Journal of medicine and lifeArticle
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe simultaneously increased prevalence of atopic diseases and decreased prevalence of infectious diseases might point to a link between the two entities. Past work mainly focused on either atopic diseases or recurrent infections. We aim to investigate whether risk factors for atopic diseases (ie, asthma, allergic rhinitis, atopic dermatitis, and/or food allergy) differ from risk factors for recurrent respiratory tract infections (RRTIs) in children.
methodsCross-sectional data were used from 5517 children aged 1 to 18 years who participated in an Electronic Portal for children between 2011 and 2019. Univariable/multivariable logistic regression analyses were performed to determine risk factors for any atopic disease and RRTIs.
resultsChildren aged ≥5 years were more likely to have any atopic disease (adjusted odds ratio [OR]: 1.50-2.77) and less likely to have RRTIs (OR: 0.68-0.84) compared to children aged less than 5 years. Female sex (OR: 0.72; 95% confidence interval [CI]: 0.63-0.81), low birth weight (OR: 0.74; 95% CI: 0.57-0.97) and dog ownership (OR: 0.79; 95% CI: 0.66-0.95) reduced the odds of any atopic disease, but not of RRTIs. Daycare attendance (OR: 1.22; 95% CI: 1.02-1.47) was associated with RRTIs, but not with atopic diseases. A family history of asthma, allergic rhinitis, atopic dermatitis, and RRTIs was significantly associated with the same entity in children, with OR varying from 1.58 (95% CI: 1.35-1.85) in allergic rhinitis to 2.20 (95% CI: 1.85-2.61) in asthma.
conclusionRisk factors for atopic diseases are distinct from risk factors for RRTIs, suggesting that the changing prevalence of both entities is not related to shared risk factors.
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