Evidence map›Paper›PMID 32841422›Full record

ArticleJournal of clinical laboratory analysis2020

The evaluation of low cut-off index values of Elecsys

Zhuoyun Tang, Yu Gou, Keyi Zhang, Zhongyi Zhao, Yinhao Wei, Dongdong Li, Li Chen, Chuanmin Tao

Abstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  4. The evaluation of low cut-off index values of ElecsysJournal of clinical laboratory analysis · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhuoyun TangDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.
Yu GouDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.
Keyi ZhangDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.
Zhongyi ZhaoDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.
Yinhao WeiDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-6137-4872
Dongdong LiDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-0290-6485
Li ChenDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.
Chuanmin TaoDepartment of Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-5332-0062

Funding

Science and Technology Planning Project of Sichuan 2020YFS0136Sichuan Province Health and Family Planning Commission Sichuan Health Office issued [2017] 70
6 · The paper itself

Abstract

objectiveTo analyze the results of different cut-off index (COI) values of Elecsys

methodsWe conducted a retrospective study of samples analyzed by Elecsys

resultsA total of 379 122 samples were analyzed. 2528 (0.67%) were positive by Elecsys

conclusionSamples with low COI values, especially those contain confounding factors, need to be further scrutinized to determine whether the confounding factors may cause false-positive problem. In addition, the hypothesis that low COI values may predict false-positive results is valid.

Indexed as

ImmunoassayAlgorithmsFalse Positive ReactionsFemaleHIV AntibodiesHIV AntigensHIV InfectionsHumansMaleReference ValuesRetrospective StudiesHIV AntibodiesHIV Antigenscut-off indexElecsys® HIV combi PT assayfalse-positiveHIV

Identifiers

PMID32841422
PMCPMC7676207

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.