Evidence map›Paper›PMID 32841279›Full record

ArticlePLoS neglected tropical diseases2020

Clinical, parasitological and molecular profiles of Cutaneous Leishmaniasis and its associated factors among clinically suspected patients attending Borumeda Hospital, North-East Ethiopia.

Habtye Bisetegn, Ayalew Jejaw Zeleke, Endalamaw Gadisa, Girma Shumie, Demekech Damte, Tiruework Fenta, Sinkinesh Behaksra, Abebe Genetu Bayih

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Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Habtye BisetegnDepartment of Medical Laboratory science, College of Medicine and Health Sciences, Wollo University,Dessie, Ethiopia.ORCID 0000-0003-3647-5924
Ayalew Jejaw ZelekeDepartment of Medical Parasitology, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia.
Endalamaw GadisaArmauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia.
Girma ShumieArmauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia.ORCID 0000-0002-8131-3564
Demekech DamteArmauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia.
Tiruework FentaArmauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia.
Sinkinesh BehaksraArmauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia.
Abebe Genetu BayihDepartment of Medical Parasitology, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia.
Armauer Hansen Research Institute · ETUniversity of Gondar · ETWollo University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCutaneous leishmaniasis is one of the most neglected tropical diseases increasing in its public health importance. In Ethiopia over 28 million people are living at risk of infection.

methodInstitution based cross-sectional study was conducted at Borumeda Hospital from February to May 2019. A total 205 leishmaniasis suspected patients were included by systematic random sampling technique. Socio demographic characteristics were collected using pre-tested questionnaires. Parasitological investigation was done from skin slit sample by using Geimsa staining method. Species identification was done by PCR-RFLP. Data were entered in to EpiData version 3.1 and analyzed using SPSS version 20 software. P-value of ≤ 0.05 was considered as statistically significant.

resultA total of 205 participants consisting 59% male and 41% female included in this study. The mean age (±SD) of the study participants was 31.9 (±14.29). The overall prevalence of cutaneous leishmaniasis was 22.4% (46/205). The prevalence in males (13.7%) was higher than in females (8.8%). It was more prevalent in the age group 16-45years old (15.6%). Clinically, 60% of patients' hade single lesion with 1.55 average number of lesions. About 30.7% of patients' had indurated plaque type of lesion. Most of the lesions were found on head and face (59%). House near to farmland, presence of hyrax in the village and presence of other cutaneous leishmaniasis cases in the neighborhood were independent predicator of cutaneous leishmaniasis prevalence. L.aethopica was found to be the etiologic agent of cutaneous leishmaniasis in the study participants.

conclusionThe prevalence of cutaneous leishmaniasis was 22.4%, this alerts the need of intervention. It is statistically associated with house near to farm land, presence of other cutaneous leishmaniasis cases in the neighborhood and presence of hyrax in village. Head and face were the most common sites of lesion.

Indexed as

AdolescentAdultAgedChildChild, PreschoolCross-Sectional StudiesDNA, ProtozoanEthiopiaFemaleHumansLeishmaniaLeishmaniasis, CutaneousMaleMiddle AgedPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthDNA, Protozoan

Identifiers

PMID32841279
PMCPMC7473553
OpenAlexW3080197253

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.