ArticleLa Radiologia medica2021
Identification of bone marrow edema of the knee: diagnostic accuracy of dual-energy CT in comparison with MRI.
Article in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of dual-energy CT for bone marrow edema in patients with acute knee injury: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Dual-energy CT for detection of knee fractures as alternative to MRI.Skeletal radiology · 2026Review
- Bone-marrow edema estimation with a microwave imaging open-ended coaxial probe array in ex vivo bovine long bones: comparison with CT.European radiology experimental · 2026Article
- Dual-Energy Computed Tomography for the Detection of Bone Edema-Like Lesions in the Equine Foot: Standing Horses and Cadaveric Specimens.Veterinary sciences · 2025Article
- Beyond the Signal: Imaging Insights and Diagnostic Relevance of Bone Oedema in Bone Tumours and Tumour-like Lesions.Cancers · 2025Review
- Dual-energy CT-derived virtual noncalcium imaging to assess bone marrow lesions in patients with knee osteoarthritis.Scientific reports · 2025Article
- Toward the Application of Dual-Energy Computed Tomography with Virtual Non-Hydroxyapatite Color-Coded Maps to Identify Traumatic Fractures in Daily Emergency Settings.Journal of imaging · 2024Article
- Bone marrow edema of the knee: a narrative review.Archives of orthopaedic and trauma surgery · 2024Review
- The Clinical Utility of Lower Extremity Dual-Energy CT Angiography in the Detection of Bone Marrow Edema in Diabetic Patients with Peripheral Artery Disease.Journal of clinical medicine · 2024Article
- Dual-Energy CT in Oncologic Imaging.Tomography (Ann Arbor, Mich.) · 2024Review
- Article
- A Comparison of Dual-Energy CT with MRI in the Detection of Traumatic Bone Marrow Edema in Distal Extremity Bones.Journal of clinical practice and research · 2023Article
- Dual-Energy CT Arthrography: Advanced Muscolo-Skelatal Applications in Clinical Practice.Tomography (Ann Arbor, Mich.) · 2023Review
- Preliminary evaluation of dual-energy CT to quantitatively assess bone marrow edema in patients with diabetic foot ulcers and suspected osteomyelitis.European radiology · 2023Article
- Computed Tomography Urography: State of the Art and Beyond.Tomography (Ann Arbor, Mich.) · 2023Review
- Traumatic bone marrow lesions in dual-energy computed tomography.Insights into imaging · 2022Review
- Heart Failure and Cardiomyopathies: CT and MR from Basics to Advanced Imaging.Diagnostics (Basel, Switzerland) · 2022Review
- Lymph Nodes Evaluation in Rectal Cancer: Where Do We Stand and Future Perspective.Journal of clinical medicine · 2022Review
- Identification of Traumatic Bone Marrow Oedema: The Pearls and Pitfalls of Dual-Energy CT (DECT).Tomography (Ann Arbor, Mich.) · 2021Article
- Identification of Non-Traumatic Bone Marrow Oedema: The Pearls and Pitfalls of Dual-Energy CT (DECT).Tomography (Ann Arbor, Mich.) · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo assess the diagnostic accuracy of dual-energy computed tomography (DECT) in diagnosing bone marrow edema (BME) of the knee in traumatic and non-traumatic patients.
methodsThis prospective IRB approved study included 33 consecutive patients (20 males, 13 females; mean age of 52.2 years) evaluated with DECT (80 and 150 kV) and MRI within 6 days. Two experienced radiologists qualitatively and quantitatively evaluated DECT images. The accuracy values were calculated by using receiver operator curves (ROC) and area under the curve (AUC), using MRI as the reference standard. Inter-observer and intra-observer agreement were calculated with k-statistics. A p < 0.05 was considered statistically significant.
resultsMRI depicted BME in 25/33 patients (75.7%). The sensitivity, specificity, PPV, NPV, and accuracy of per-partition qualitative analysis were 92.9, 92.9, 78.2, 97.9, and 92.9%, for reader 1, and 88.2, 93.9, 79.8, 96.6, and 92.6%, for reader 2, respectively. The inter-observer agreement was substantial (k = 0.793) and the intra-observer agreement was near-perfect (k = 0.844). At the quantitative analysis, a significant difference (p < 0.001) was depicted between the density values of positive (mean 3.6 ± 25.3 HU) and negative cases (mean - 72.2 ± 45.1 HU). By using - 15 HU cutoff to identify BME, sensitivity, specificity, PPV, NPV, and accuracy of DECT were 84.7, 93.6, 78.2, 95.7, and 91.6%, respectively.
conclusionDECT can accurately identify BME of the knee.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.