Evidence map›Paper›PMID 32840676›Full record

ArticleDiabetologia2020

Preserved Ca

Francisco Jaque-Fernandez, Agathe Beaulant, Christine Berthier, Laloé Monteiro, Bruno Allard, Mariana Casas, Jennifer Rieusset, Vincent Jacquemond

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Diabetologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. A new set of equations for the simplified calibration of fluorescence CaJournal of muscle research and cell motility · 2021
    Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Francisco Jaque-FernandezInstitut NeuroMyoGène, UMR CNRS 5310 - Inserm U1217 - Université Claude Bernard Lyon 1 - Univ Lyon, Faculté de Médecine et de Pharmacie, Lyon, France.
Agathe BeaulantCarMeN Laboratory, Inserm, INRA, INSA Lyon, Université Claude Bernard Lyon 1 - Univ Lyon, Pierre-Bénite, France.
Christine BerthierInstitut NeuroMyoGène, UMR CNRS 5310 - Inserm U1217 - Université Claude Bernard Lyon 1 - Univ Lyon, Faculté de Médecine et de Pharmacie, Lyon, France.ORCID 0000-0002-9608-643X
Laloé MonteiroInstitut NeuroMyoGène, UMR CNRS 5310 - Inserm U1217 - Université Claude Bernard Lyon 1 - Univ Lyon, Faculté de Médecine et de Pharmacie, Lyon, France.
Bruno AllardInstitut NeuroMyoGène, UMR CNRS 5310 - Inserm U1217 - Université Claude Bernard Lyon 1 - Univ Lyon, Faculté de Médecine et de Pharmacie, Lyon, France.ORCID 0000-0002-7131-7828
Mariana CasasPrograma de Fisiología y Biofísica, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.ORCID 0000-0002-6930-311X
Jennifer RieussetCarMeN Laboratory, Inserm, INRA, INSA Lyon, Université Claude Bernard Lyon 1 - Univ Lyon, Pierre-Bénite, France.ORCID 0000-0002-1587-2253
Vincent JacquemondInstitut NeuroMyoGène, UMR CNRS 5310 - Inserm U1217 - Université Claude Bernard Lyon 1 - Univ Lyon, Faculté de Médecine et de Pharmacie, Lyon, France. vincent.jacquemond@univ-lyon1.fr.ORCID 0000-0003-4944-270X
Université Claude Bernard Lyon 1 · FRUniversity of Chile · CL

Funding

Centre National de la Recherche Scientifique grant to Institut NeuroMyoGèneCONYCIT PhD fellowship to F. Jaque FernandezECOS-CONICYT C13B01Institut National de la Santé et de la Recherche Médicale grant to Institut NeuroMyoGèneMinistère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche PhD fellowship to A. BeaulantUniversité Claude Bernard - Lyon 1 grant to Institut NeuroMyoGène
6 · The paper itself

Abstract

aims/hypothesisDisrupted intracellular Ca

methodsIntact muscle fibres were isolated from mice fed either with a standard chow diet or with a high-fat, high-sucrose diet generating obesity, insulin resistance and glucose intolerance. Properties of muscle fibres were investigated with a combination of whole-cell voltage-clamp electrophysiology and confocal fluorescence imaging. The integrity and density of the plasma membrane network (transverse tubules) that carries the membrane excitation throughout the muscle fibres was assessed with the dye Di-8-ANEPPS. Ca

resultsThe transverse tubule network architecture and density were well preserved in the fibres from the obese mice. The Ca CONCLUSIONS/

interpretationThe functional properties of the main mechanisms involved in the control of muscle Ca

Indexed as

AnimalsCalciumCalcium SignalingCell MembraneDiabetes Mellitus, Type 2MiceMice, ObeseMuscle, SkeletalSarcoplasmic ReticulumCalciumCa2+ homeostasisCytosolic Ca2+ clearanceExcitation–contraction couplingObesityRyanodine receptorSarcoplasmic reticulum Ca2+ releaseSkeletal muscleType 2 diabetes

Identifiers

PMID32840676
OpenAlexW3080762967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.