Evidence map›Paper›PMID 32840226›Full record

ArticleInternational journal of stem cells2020

KLF4 Regulates Goblet Cell Differentiation in BMI1

Takahito Katano, Agnieszka B Bialkowska, Vincent W Yang

Open access · diamondAbstract read
In one paragraph

Article in International journal of stem cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cells · 2025
    Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Takahito KatanoDepartment of Medicine, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA.
Agnieszka B BialkowskaDepartment of Medicine, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA.
Vincent W YangDepartment of Medicine, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA.
Stony Brook School · USStony Brook University · US

Funding

REGULATION OF INTESTINAL EPITHELIAL CELL PROLIFERATIONR01DK052230 · NIDDK · STATE UNIVERSITY NEW YORK STONY BROOK · PI Vincent W Yang · 1997 to 2026
$8.7M
MECHANISMS OF INTESTINAL TUMORIGENESISR01CA084197 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI YANG, VINCENT W · 2000 to 2020
$7.5M
NCI NIH HHS R01 CA084197NIDDK NIH HHS R01 DK052230
6 · The paper itself

Abstract

Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor, expressed in villus cells of the intestinal epithelium, that promotes cellular differentiation and tissue homeostasis. Previous studies suggest that BMI1

Indexed as

Goblet cellIntestinal stem cellKrüppel-like factor 4Mucin 2

Identifiers

PMID32840226
PMCPMC7691855
OpenAlexW3080701984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.