Evidence map›Paper›PMID 32840068›Full record

ArticleJournal of biomedical optics2020

Toward accurate quantitative photoacoustic imaging: learning vascular blood oxygen saturation in three dimensions.

Ciaran Bench, Andreas Hauptmann, Ben Cox

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
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  5. Depth-dependent fluence compensation withoutJournal of biomedical optics · 2025
    Article
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  9. Current trends in the characterization and monitoring of vascular response to cancer therapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  10. Article
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  14. Article
  15. Review
  16. Article
  17. Functional Photoacoustic Imaging for Placental Monitoring: A Mini Review.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Review
  18. Review of Deep Learning Approaches for Interleaved Photoacoustic and Ultrasound (PAUS) Imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Ciaran BenchUniv. College London, United Kingdom.
Andreas HauptmannUniv. of Oulu, Finland.
Ben CoxUniv. College London, United Kingdom.
University College London · GB

Funding

Biotechnology and Biological Sciences Research Council
6 · The paper itself

Abstract

significanceTwo-dimensional (2-D) fully convolutional neural networks have been shown capable of producing maps of sO2 from 2-D simulated images of simple tissue models. However, their potential to produce accurate estimates in vivo is uncertain as they are limited by the 2-D nature of the training data when the problem is inherently three-dimensional (3-D), and they have not been tested with realistic images.

aimTo demonstrate the capability of deep neural networks to process whole 3-D images and output 3-D maps of vascular sO2 from realistic tissue models/images. APPROACH: Two separate fully convolutional neural networks were trained to produce 3-D maps of vascular blood oxygen saturation and vessel positions from multiwavelength simulated images of tissue models.

resultsThe mean of the absolute difference between the true mean vessel sO2 and the network output for 40 examples was 4.4% and the standard deviation was 4.5%.

conclusions3-D fully convolutional networks were shown capable of producing accurate sO2 maps using the full extent of spatial information contained within 3-D images generated under conditions mimicking real imaging scenarios. We demonstrate that networks can cope with some of the confounding effects present in real images such as limited-view artifacts and have the potential to produce accurate estimates in vivo.

Indexed as

ArtifactsNeural Networks, ComputerOxygenImaging, Three-DimensionalOximetryOxygendeep learningmachine learningoxygen saturationphotoacousticsquantitative photoacousticssO2

Identifiers

PMID32840068
PMCPMC7443711
OpenAlexW3080539213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.