Evidence map›Paper›PMID 32839952›Full record

ArticleJournal of neurovirology2020

Progressive multifocal leukoencephalopathy in an HIV patient was diagnosed by 3 times lumbar punctures and 2 times brain biopsies.

Mengyan Wang, Zhongdong Zhang, Jinchuan Shi, Hong Liu, Binhai Zhang, Jun Yan

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurovirology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mengyan WangXixi Hospital of Hangzhou, Hangzhou, 310023, China.
Zhongdong ZhangXixi Hospital of Hangzhou, Hangzhou, 310023, China.
Jinchuan ShiXixi Hospital of Hangzhou, Hangzhou, 310023, China.
Hong LiuXixi Hospital of Hangzhou, Hangzhou, 310023, China.
Binhai ZhangXixi Hospital of Hangzhou, Hangzhou, 310023, China.
Jun YanXixi Hospital of Hangzhou, Hangzhou, 310023, China. 18989847860@126.com.ORCID 0000-0002-3910-5104
Hangzhou Xixi hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease of the central nervous system caused by JC virus (JCV) and is difficult to diagnose. We report on a male HIV-positive patient with PML finally diagnosed by 3 times lumbar punctures and 2 times brain biopsies. Negative results of JCV-PCR in cerebrospinal fluid (CSF) do not rule out the diagnosis of PML when clinical manifestations and neuroimaging features suspected PML. It is necessary to obtain new CSF and make repeat tests and even perform brain biopsy.

Indexed as

BrainCoinfectionDNA, ViralFatal OutcomeHIVHIV InfectionsHumansJC VirusLeukoencephalopathy, Progressive MultifocalMagnetic Resonance ImagingMaleMiddle AgedSpinal CordSpinal PunctureDNA, ViralHIVJC virusProgressive multifocal leukoencephalopathy

Identifiers

PMID32839952
PMCPMC7716907
OpenAlexW3081332387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.