Evidence map›Paper›PMID 32839860›Full record

ArticleMikrochimica acta2020

A competitive immunoassay based on engineered magnetic/fluorescent nanoparticles and biolayer interferometry-based assay for T-2 toxin determination.

Yafan Li, Li Xu, Xiaochen Fu, Hongxiang Liu, Guo-Bin Ding, Lin Song Li, Jinming Zhu, Yi Guo

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yafan LiKey Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, 130012, People's Republic of China.
Li XuKey Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, 130012, People's Republic of China. xuli@jlu.edu.cn.ORCID http://orcid.org/0000-0001-5378-8020
Xiaochen FuKey Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, 130012, People's Republic of China.
Hongxiang LiuKey Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, 130012, People's Republic of China.
Guo-Bin DingInstitute of Biotechnology, The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan, 030006, People's Republic of China. dinggb2012@sxu.edu.cn.
Lin Song LiKey Laboratory for Special Functional Materials, the Ministry of Education, Henan University, Kaifeng, 475004, People's Republic of China.
Jinming ZhuChina-Japan Union Hospital of Jilin University, Changchun, 130033, People's Republic of China.
Yi GuoKey Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, 130012, People's Republic of China.
Jilin University · CNHenan University · CNShanxi University · CN

Funding

National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology (CN) 2012ZX09503001-003National Natural Science Foundation of China 81771965, 31571017, 81571791, 81271697Science and Technology Department of Jilin Province, China 20170204027NY, 20130206069GXSpecial Project of Biological Medicine of Jilin Province, China SXGJSF2017-1
6 · The paper itself

Abstract

For the first time a competitive immunoassay was developed by employing T-2 antibody-functionalized magnetite nanoparticles and T-2 toxin-conjugated fluorescent quantum dots (QDs). Free T-2 and the T-2-modified QDs compete for binding to antibody-modified magnetic beads; the magnetic beads collected by magnetic separation were subjected to fluorescence intensity analysis (with excitation/emission wavelengths at 460/616 nm). This competitive immunoassay for T-2 toxin determination was applied both in a microcentrifuge tube and on a 96-well plate. The dynamic range of the immunoassay is 1-100 ng mL

Indexed as

AnimalsAntibodies, ImmobilizedCattleFluorescent DyesFood ContaminationHordeumImmunoassayInterferometryLimit of DetectionMagnetite NanoparticlesPolystyrenesQuantum DotsSerum Albumin, BovineT-2 ToxinAntibodies, ImmobilizedFluorescent DyesMagnetite NanoparticlesPolystyrenesSerum Albumin, BovineT-2 ToxinBiolayer interferometryCompetitive immunoassayMagnetic polystyrene nanospheresQuantum dotsT-2 toxin determination

Identifiers

PMID32839860
OpenAlexW3080421385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.