Evidence map›Paper›PMID 32839838›Full record

SynthesisJournal of neurology2021

Risk factors for benign paroxysmal positional vertigo recurrence: a systematic review and meta-analysis.

Jinbao Chen, Senlin Zhang, Kai Cui, Chuxuan Liu

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 6 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 6 syntheses or guidelines pooled it, 118 citations in OpenAlex.

  1. Seasonal and monthly variation in benign paroxysmal positional vertigo: a systematic review and meta‑analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
  2. Seasonal and monthly variation in benign paroxysmal positional vertigo: a systematic review and meta‑analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Article
  10. Reduced vagal reserve in benign paroxysmal positional vertigo: preliminary results of a case-control HRV study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Observational
  11. Gans repositioning maneuver in treating posterior canal benign paroxysmal positional vertigo: A systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  12. Article
  13. Article
  14. Recurrence of benign paroxysmal positional vertigo: risk factors and outcomes.Revista da Associacao Medica Brasileira (1992) · 2026
    Article
  15. Environmental drivers of vertigo.Environmental health and preventive medicine · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jinbao ChenDepartment of Pediatrics, The First Clinic College of Xinxiang Medical University, Xinxiang, 453000, Henan, China. chenjinbao999@126.com.ORCID http://orcid.org/0000-0002-1226-1457
Senlin ZhangDepartment of Pediatrics, The First Clinic College of Xinxiang Medical University, Xinxiang, 453000, Henan, China.
Kai CuiDepartment of Pediatrics, The First Clinic College of Xinxiang Medical University, Xinxiang, 453000, Henan, China.
Chuxuan LiuDepartment of Imaging, The First Clinic College of Xinxiang Medical University, Xinxiang, 453000, Henan, China.
Xinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeBenign paroxysmal positional vertigo is one of the most common vestibular diseases, especially in the elderly. Although the treatment of BPPV is relatively successful, many patients suffer recurrence after treatment. Therefore, identifying potential risk factors for BPPV recurrence may help improve treatment outcome and patient prognosis. However, some related risk factors for BPPV recurrence are relatively controversial and poorly studied. This meta-analysis aims to identify potential risk factors associated with BPPV recurrence, thereby reducing the recurrence rate of BPPV and improving the prognosis of patients.

methodsThis meta-analysis was conducted through systematically searching PubMed, Embase, and the Cochrane Library for eligible English original studies published up to June 2020. All search results were reviewed based on our inclusion and exclusion criteria. We calculated the pooled odds ratios (ORs) or the mean differences (MDs) with their corresponding 95% confidence intervals (CIs) to evaluate the effects of included risk factors on BPPV recurrence.

resultsA total of 14 studies involving 3060 BPPV patients published between 2010 and 2019 were finally included, including six prospective studies and eight retrospective studies, with a NOS score ranged from 6 to 9. Our pooled results of this meta-analysis suggested that the recurrence of BPPV was closely related to female gender (OR = 1.42; 95% CI 1.17-1.74; P = 0.0004), hypertension (OR = 2.61; 95% CI 1.22-5.59; P = 0.01), diabetes mellitus (OR = 2.62; 95% CI 1.25-5.48; P = 0.01), hyperlipidemia (OR = 1.60; 95% CI 1.23-2.09; P = 0.0006), osteoporosis (OR = 1.72; 95% CI 1.03-2.88; P = 0.04) and vitamin D deficiency (MD = - 3.29; 95% CI - 5.32 to - 1.26; P = 0.001).

conclusionThis meta-analysis indicated that female gender, hypertension, diabetes mellitus, hyperlipidemia, osteoporosis, and vitamin D deficiency were risk factors for BPPV recurrence. However, the effects of other potential risk factors including advanced age, migraine, head trauma, and Menière's disease on BPPV recurrence need further investigations. Furthermore, most studies included in this meta-analysis were performed in Asia, so our results cannot easily be extended to the whole world population. Therefore, more large-scale prospective studies in different countries are required to further investigate these risk factors.

Indexed as

Benign Paroxysmal Positional VertigoAgedFemaleHumansProspective StudiesRecurrenceRetrospective StudiesRisk FactorsBenign paroxysmal positional vertigoMeta-analysisRecurrenceRisk factorsSystematic review

Identifiers

PMID32839838
OpenAlexW3081254294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.