ReviewNature reviews. Neuroscience2020
Multidimensional processing in the amygdala.
Review in Nature reviews. Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
90 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A neuroimaging meta-analysis on social impression formation of stable characteristics.Cerebral cortex (New York, N.Y. : 1991) · 2026Pooled it
- The effects of childhood adversity: Two specific neural patterns.Neuroscience and biobehavioral reviews · 2025Pooled it
- Oxytocinergic Modulation of Stress-Associated Amygdala-Hippocampus Pathways in Humans Is Mediated by Serotonergic Mechanisms.The international journal of neuropsychopharmacology · 2022Trial
- Decreased amygdala volume in adults after premature birth.Scientific reports · 2021Trial
- Cannabinoid modulation of central amygdala population dynamics during threat investigation.Nature communications · 2026Article
- Comparative neuroanatomy of emotion expression: from flies to humans.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- Weakening of Subcortical and Strengthening of Cortical Visual Pathways Across Early Adolescence.Human brain mapping · 2026Article
- Social Dysfunction in ADHD Children Associated With Increased Amygdala Functional Connectivity Instability: A Static and Dynamic Functional Connectivity Study.CNS neuroscience & therapeutics · 2026Article
- The Amygdala and Politics.Brain sciences · 2026Review
- Right amygdala ablation reduces maladaptive negative interpretation bias and symptoms in a patient with post-traumatic stress disorder.Nature communications · 2026Article
- Computational neural dynamics of goal-directed visual attention in macaques.Science advances · 2026Article
- An fMRI-informed EEG model of the amygdala is associated with salience network dynamics during naturalistic emotional stimulation.Molecular psychiatry · 2026Article
- Novelty, Ecological Relevance, and Sexual Receptivity Modulate Neuronal Interactions between the Amygdala and Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Value coding by primate amygdala neurons complies with the continuity axiom of economic choice theory.Journal of neurophysiology · 2026Article
- State and trait serotonin variations interact to shape the intrinsic connectivity and gradient architecture of the brain - a combined TPH2 genetics and tryptophan depletion study in men.Psychopharmacology · 2026Article
- Region-resolved proteomic map of the human brain: functional interconnections and neurological implications.Signal transduction and targeted therapy · 2026Article
- Saccade-related LFP power transients in the primate amygdala and hippocampus linked to the perception of social status.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Huntingtin in the amygdaloid basolateral complex is correlated with Vonsattel staging in Huntington's disease.Brain communications · 2026Article
- Prenatal fentanyl exposure affects social dominance and myelination patterns in the adult mouse brain.Neuropharmacology · 2025Article
- Outdoor Air Pollution Is Related to Amygdala Subregion Volume and Apportionment in Early Adolescence.Biological psychiatry global open science · 2025Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Brain-wide circuits that coordinate affective and social behaviours intersect in the amygdala. Consequently, amygdala lesions cause a heterogeneous array of social and non-social deficits. Social behaviours are not localized to subdivisions of the amygdala even though the inputs and outputs that carry social signals are anatomically restricted to distinct subnuclear regions. This observation may be explained by the multidimensional response properties of the component neurons. Indeed, the multitudes of circuits that converge in the amygdala enlist the same subset of neurons into different ensembles that combine social and non-social elements into high-dimensional representations. These representations may enable flexible, context-dependent social decisions. As such, multidimensional processing may operate in parallel with subcircuits of genetically identical neurons that serve specialized and functionally dissociable functions. When combined, the activity of specialized circuits may grant specificity to social behaviours, whereas multidimensional processing facilitates the flexibility and nuance needed for complex social behaviour.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.