ArticleScientific reports2020
Exhaled breath compositions under varying respiratory rhythms reflects ventilatory variations: translating breathomics towards respiratory medicine.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Physio-metabolic and clinical consequences of wearing face masks-Systematic review with meta-analysis and comprehensive evaluation.Frontiers in public health · 2023Pooled it
- Preparation of dual mode spectroscopic system for testing: Analysis of sample holder and investigation of intensity noise.Heliyon · 2025Article
- Exhaled breath metabolites reveal postmenopausal gut-bone cross-talk and non-invasive markers for osteoporosis.Communications medicine · 2024Article
- Article
- Analysis of Bacterial Metabolites in Breath Gas of Critically Ill Patients for Diagnosis of Ventilator-Associated Pneumonia-A Proof of Concept Study.Biomolecules · 2024Article
- Article
- Effects of Contagious Respiratory Pathogens on Breath Biomarkers.Antioxidants (Basel, Switzerland) · 2024Article
- Multiwavelength Photoacoustic Breath Analysis Sensor for the Diagnosis of Lung Diseases: COPD and Asthma.ACS sensors · 2023Article
- Origin of breath isoprene in humans is revealed via multi-omic investigations.Communications biology · 2023Article
- Dynamic Stability of Volatile Organic Compounds in Respiratory Air in Schizophrenic Patients and Its Potential Predicting Efficacy of TAAR Agonists.Molecules (Basel, Switzerland) · 2023Article
- Exhaled Air Metabolome Analysis for Pulmonary Arterial Hypertension Fingerprints Identification-The Preliminary Study.International journal of environmental research and public health · 2022Article
- Advanced setup for safe breath sampling and patient monitoring under highly infectious conditions in the clinical environment.Scientific reports · 2022Article
- Profiling of exhaled volatile organics in the screening scenario of a COVID-19 test center.iScience · 2022Article
- Effects of COVID-19 protective face masks and wearing durations on respiratory haemodynamic physiology and exhaled breath constituents.The European respiratory journal · 2022Article
- Fast and noninvasive electronic nose for sniffing out COVID-19 based on exhaled breath-print recognition.NPJ digital medicine · 2022Article
- Hybrid learning method based on feature clustering and scoring for enhanced COVID-19 breath analysis by an electronic nose.Artificial intelligence in medicine · 2022Article
- Physiological and metabolic effects of healthy female aging on exhaled breath biomarkers.iScience · 2022Article
- A comparison of alternative selection methods for reporting spirometric parameters in healthy adults.Scientific reports · 2021Article
- Breathing Rhythm Variations during Wash-In Do Not Influence Exhaled Volatile Organic Compound Profile Analyzed by an Electronic Nose.Molecules (Basel, Switzerland) · 2021Article
- Is a Mask That Covers the Mouth and Nose Free from Undesirable Side Effects in Everyday Use and Free of Potential Hazards?International journal of environmental research and public health · 2021Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Control of breathing is automatic and its regulation is keen to autonomic functions. Therefore, involuntary and voluntary nervous regulation of breathing affects ventilatory variations, which has profound potential to address expanding challenges in contemporary pulmonology. Nonetheless, the fundamental attributes of the aforementioned phenomena are rarely understood and/or investigated. Implementation of unconventional approach like breathomics may leads to a better comprehension of those complexities in respiratory medicine. We applied breath-resolved spirometry and capnometry, non-invasive hemodynamic monitoring along with continuous trace analysis of exhaled VOCs (volatile organic compounds) by means of real-time mass-spectrometry in 25 young and healthy adult humans to investigate any possible mirroring of instant ventilatory variations by exhaled breath composition, under varying respiratory rhythms. Hemodynamics remained unaffected. Immediate changes in measured breath compositions and corresponding variations occurred when respiratory rhythms were switched between spontaneous (involuntary/unsynchronised) and/or paced (voluntary/synchronised) breathing. Such changes in most abundant, endogenous and bloodborne VOCs were closely related to the minute ventilation and end-tidal CO
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