ArticleNature communications2020
Grid cells are modulated by local head direction.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Medial entorhinal VIP-expressing interneurons receive input from the thalamic anterior dorsal nucleus and are critical for spatial memory.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Tracking the topology of neural manifolds across populations.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A topological deep learning framework for neural spike decoding.Biophysical journal · 2024Article
- Article
- Article
- Article
- Variational log-Gaussian point-process methods for grid cells.Hippocampus · 2023Article
- Cortical Integration of Vestibular and Visual Cues for Navigation, Visual Processing, and Perception.Annual review of neuroscience · 2023Review
- Superficial-layer versus deep-layer lateral entorhinal cortex: Coding of allocentric space, egocentric space, speed, boundaries, and corners.Hippocampus · 2023Article
- Effects of neuromodulation-inspired mechanisms on the performance of deep neural networks in a spatial learning task.iScience · 2023Article
- Impaired Spatial Firing Representations of Neurons in the Medial Entorhinal Cortex of the Epileptic Rat Using Microelectrode Arrays.Research (Washington, D.C.) · 2023Article
- cFOS as a biomarker of activity maturation in the hippocampal formation.Frontiers in neuroscience · 2023Article
- Article
- Grid cell remapping under three-dimensional object and social landmarks detected by implantable microelectrode arrays for the medial entorhinal cortex.Microsystems & nanoengineering · 2022Article
- The grid code for ordered experience.Nature reviews. Neuroscience · 2021Review
- Identification of predictors for mini-mental state examination and revised Hasegawa's Dementia Scale scores using MR-based brain morphometry.European journal of radiology open · 2021Article
- Orientation Invariant Sensorimotor Object Recognition Using Cortical Grid Cells.Frontiers in neural circuits · 2021Article
- A Model of Spatial Cell Development in Rat Hippocampus Based on Artificial Neural Network.Journal of healthcare engineering · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Grid and head direction codes represent cognitive spaces for navigation and memory. Pure grid cells generate grid codes that have been assumed to be independent of head direction, whereas conjunctive cells generate grid representations that are tuned to a single head direction. Here, we demonstrate that pure grid cells also encode head direction, but through distinct mechanisms. We show that individual firing fields of pure grid cells are tuned to multiple head directions, with the preferred sets of directions differing between fields. This local directional modulation is not predicted by previous continuous attractor or oscillatory interference models of grid firing but is accounted for by models in which pure grid cells integrate inputs from co-aligned conjunctive cells with firing rates that differ between their fields. We suggest that local directional signals from grid cells may contribute to downstream computations by decorrelating different points of view from the same location.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.