Evidence map›Paper›PMID 32839436›Full record

ArticleNature communications2020

Tissue sodium excess is not hypertonic and reflects extracellular volume expansion.

Giacomo Rossitto, Sheon Mary, Jun Yu Chen, Philipp Boder, Khai Syuen Chew, Karla B Neves, Rheure L Alves, Augusto C Montezano, Paul Welsh, Mark C Petrie and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 91 citations in OpenAlex.

  1. Trial
  2. Salt and chronic kidney disease.Nature reviews. Nephrology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Diuretics in patients with chronic kidney disease.Nature reviews. Nephrology · 2025
    Review
  10. Review
  11. Article
  12. Epithelial Na+ Channels, Immune Cells, and Salt.Annual review of physiology · 2025
    Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Vascular mechanotransduction.Physiological reviews · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Giacomo Rossitto *Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK. Giacomo.Rossitto@glasgow.ac.uk.ORCID http://orcid.org/0000-0001-9023-0835
Sheon Mary *Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0001-9392-3020
Jun Yu Chen *Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0002-1823-8282
Philipp BoderInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0003-3595-6865
Khai Syuen ChewInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0001-7750-2998
Karla B NevesInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0001-5158-9263
Rheure L AlvesInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Augusto C MontezanoInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Paul WelshInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Mark C PetrieInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Delyth GrahamInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Rhian M TouyzInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0003-0670-0887
Christian DellesInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.ORCID http://orcid.org/0000-0003-2238-2612
University of Glasgow · GB

Funding

British Heart Foundation CH/4/29762British Heart Foundation RE/13/5/30177British Heart Foundation RE/18/6/34217
6 · The paper itself

Abstract

Our understanding of Na

Indexed as

AgingAnimalsEdemaFemaleHomeostasisHumansHypertensionLiverLungMaleMyocardiumOrgan SpecificityOsmolar ConcentrationPotassiumRats, Inbred WKYSkinNfat5 protein, ratPotassiumSodiumTranscription Factors

Identifiers

PMID32839436
PMCPMC7445299
OpenAlexW3080577993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.