Evidence map›Paper›PMID 32839415›Full record

ArticleInternational journal of molecular sciences2020

Revealing Metabolic Perturbation Following Heavy Methamphetamine Abuse by Human Hair Metabolomics and Network Analysis.

Suji Kim, Won-Jun Jang, Hyerim Yu, Jihyun Kim, Sang-Ki Lee, Chul-Ho Jeong, Sooyeun Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Impact of multiple substance use on circulating ST2, a biomarker of adverse cardiac remodelling, in women.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Suji KimCollege of Pharmacy, Keimyung University, 1095 Dalgubeoldaero, Dalseo-gu, Daegu 42601, Korea.
Won-Jun JangCollege of Pharmacy, Keimyung University, 1095 Dalgubeoldaero, Dalseo-gu, Daegu 42601, Korea.ORCID 0000-0001-6598-0810
Hyerim YuCollege of Pharmacy, Keimyung University, 1095 Dalgubeoldaero, Dalseo-gu, Daegu 42601, Korea.
Jihyun KimNational Forensic Service, 10, Ipchun-ro, Wonju, Gangwon-do 26460, Korea.
Sang-Ki LeeNational Forensic Service, 10, Ipchun-ro, Wonju, Gangwon-do 26460, Korea.
Chul-Ho JeongCollege of Pharmacy, Keimyung University, 1095 Dalgubeoldaero, Dalseo-gu, Daegu 42601, Korea.ORCID 0000-0003-4709-3497
Sooyeun LeeCollege of Pharmacy, Keimyung University, 1095 Dalgubeoldaero, Dalseo-gu, Daegu 42601, Korea.
Keimyung University · KRNational Forensic Institute · KR

Funding

National Research Foundation of Korea NRF-2016R1A6A1A03011325National Research Foundation of Korea NRF-2018R1D1A1B07048159
6 · The paper itself

Abstract

Methamphetamine (MA) is a highly addictive central nervous system stimulant. Drug addiction is not a static condition but rather a chronically relapsing disorder. Hair is a valuable and stable specimen for chronic toxicological monitoring as it retains toxicants and metabolites. The primary focus of this study was to discover the metabolic effects encompassing diverse pathological symptoms of MA addiction. Therefore, metabolic alterations were investigated in human hair following heavy MA abuse using both targeted and untargeted mass spectrometry and through integrated network analysis. The statistical analyses (

Indexed as

AdultAmino AcidsAmphetamineCase-Control StudiesCentral Nervous System StimulantsGlycerophospholipidsGlycosphingolipidsHairHumansLipid MetabolismMaleMetabolomicsMethamphetamineMiddle AgedPrincipal Component AnalysisSphingolipidsAmino AcidsAmphetamineCentral Nervous System StimulantsGlycerophospholipidsGlycosphingolipidsMethamphetamineSphingolipidsdrug addictionhairlipid metabolismmetabolomicsmethamphetaminenetwork analysis

Identifiers

PMID32839415
PMCPMC7503996
OpenAlexW3080862190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.