Evidence map›Paper›PMID 32839340›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Brain-wide structural and functional disruption in mice with oligodendrocyte-specific

Jad Asleh, Ben Shofty, Nadav Cohen, Alexandra Kavushansky, Alejandro López-Juárez, Shlomi Constantini, Nancy Ratner, Itamar Kahn

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Where do we stand on fMRI in awake mice?Cerebral cortex (New York, N.Y. : 1991) · 2024
    Pooled it
  3. Pooled it
  4. Article
  5. Correspondence of large-scale functional brain network decline across aging mice and humans.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
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  8. Review
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  10. Reduced myelin contributes to cognitive impairment in patients with monogenic small vessel disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
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  13. Review
  14. Article
  15. The Contribution of Oxidative Stress toAntioxidants (Basel, Switzerland) · 2023
    Review
  16. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jad AslehDepartment of Neuroscience, Rappaport Faculty of Medicine and Institute, Technion-Israel Institute of Technology, 3525422 Haifa, Israel.ORCID 0000-0003-3498-0003
Ben ShoftyDepartment of Neuroscience, Rappaport Faculty of Medicine and Institute, Technion-Israel Institute of Technology, 3525422 Haifa, Israel.
Nadav CohenDepartment of Neuroscience, Rappaport Faculty of Medicine and Institute, Technion-Israel Institute of Technology, 3525422 Haifa, Israel.
Alexandra KavushanskyDepartment of Neuroscience, Rappaport Faculty of Medicine and Institute, Technion-Israel Institute of Technology, 3525422 Haifa, Israel.
Alejandro López-JuárezDivision of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229.ORCID 0000-0003-4001-897X
Shlomi ConstantiniDepartment of Pediatric Neurosurgery and Gilbert Israeli NF Center, Tel Aviv Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6423906, Israel.
Nancy RatnerDivision of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229 Nancy.Ratner@cchmc.org kahn@technion.ac.il.
Itamar KahnDepartment of Neuroscience, Rappaport Faculty of Medicine and Institute, Technion-Israel Institute of Technology, 3525422 Haifa, Israel; Nancy.Ratner@cchmc.org kahn@technion.ac.il.ORCID 0000-0002-1895-8677
Technion – Israel Institute of Technology · ILCincinnati Children's Hospital Medical Center · USTel Aviv University · IL

Funding

Brain Dysfunction in NeurofibromatosisR01NS091037 · NINDS · CINCINNATI CHILDRENS HOSP MED CTR · PI KAHN, ITAMAR, RATNER, NANCY · 2015 to 2019
$1.6M
NINDS NIH HHS R01 NS091037
6 · The paper itself

Abstract

Neurofibromin gene (

Indexed as

BrainNeurofibromin 1AnimalsGene DeletionMagnetic Resonance ImagingMiceMice, Inbred C57BLMyelin SheathNitric OxideNitric Oxide SynthaseOligodendrogliaNeurofibromin 1Nitric OxideNitric Oxide SynthaseconnectomeNF1oligodendrocytesresting state

Identifiers

PMID32839340
PMCPMC7486714
OpenAlexW3080720409

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.