Evidence map›Paper›PMID 32838546›Full record

ArticleAIDS care2021

PrEParing for long-acting injectable PrEP in the South: perspectives from healthcare providers in Georgia.

Casey D Xavier Hall, Justin C Smith, Robert A Driggers, Bethany Stoller, Zara Khan, Jingjing Li, Elisa H Ignatius, Aaron J Siegler

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Observational
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  6. Article
  7. Article
  8. Article
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  11. Readiness to Provide Oral and Injectable PrEP for Sexual and Gender Minority Youth Among Healthcare Providers and Clinics in the U.S. Northeast.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2023
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Casey D Xavier HallInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, IL, USA.ORCID 0000-0003-1658-3717
Justin C SmithDepartment of Behavioral, Social, & Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Robert A Driggers
Bethany StollerDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Zara KhanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.ORCID 0000-0002-7624-6379
Jingjing LiDepartment of Behavioral, Social, & Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, GA, USA.ORCID 0000-0003-4652-3379
Elisa H IgnatiusJohns Hopkins School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Aaron J SieglerDepartment of Behavioral, Social, & Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Emory University · USJohns Hopkins University · USNorthwestern University · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Daniel Lingwood · 2004 to 2026
$94.4M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Hannah LF Cooper · 2002 to 2026
$74.0M
Clinical Pharmacology Training ProgramT32GM066691 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Matthew Michael Ippolito · 2003 to 2026
$6.4M
Making it last: A randomized, controlled trial of a home care system to promote persistence in PrEP careR01MH114692 · NIMH · EMORY UNIVERSITY · PI MAYER, KENNETH H, SIEGLER, AARON JULIUS · 2017 to 2021
$5.8M
NIAID NIH HHS P30 AI060354NIGMS NIH HHS T32 GM066691NIMH NIH HHS R01 MH114692
6 · The paper itself

Abstract

New modalities of Pre-exposure Prophylaxis (PrEP) such as long-acting injectable PrEP (LAI-PrEP) promise increased prevention of HIV transmission; however, similar biomedical interventions have not been met with universal adoption by healthcare providers or populations most affected by HIV. This qualitative study explores healthcare provider considerations for the rollout of LAI-PrEP. Eleven key-informant in-depth interviews were conducted with clinicians who prescribe daily oral PrEP. Participants reviewed a currently proposed LAI regimen and were asked to reflect on its implications for their clinical practice. Interviews were transcribed verbatim and thematically coded, with results organized using the Consolidated Framework for Implementation Research (CFIR). All participants expressed interest in prescribing LAI-PrEP and anticipated that at least some patients would be interested. Participants identified characteristics of the intervention, inner intervention setting, and outer intervention setting that will be influential in bringing LAI-PrEP to scale. Clinicians in the South have unique insights into the challenges of and opportunities for successful rollout of future PrEP regimens. Bringing these insights into a CFIR framework highlights the nuances surrounding LAI-PrEP, including structural concerns such as cost barriers and access to in-person healthcare services. It is critical to address these challenges to ensure successful implementation of new PrEP formulations.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisGeorgiaHealth PersonnelHumansAnti-HIV Agentshealthcare providerPrEPSouth

Identifiers

PMID32838546
PMCPMC8152107
OpenAlexW3081171312

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.