Evidence map›Paper›PMID 32838208›Full record

ArticleMedical devices & sensors2020

MADVent: A low-cost ventilator for patients with COVID-19.

Aditya Vasan, Reiley Weekes, William Connacher, Jeremy Sieker, Mark Stambaugh, Preetham Suresh, Daniel E Lee, William Mazzei, Eric Schlaepfer, Theodore Vallejos and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Medical devices & sensors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Validation of a specialized evaluation system for COVID-19 in Japan: A retrospective, multicenter cohort study.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Aditya VasanMedically Advanced Devices Laboratory Center for Medical Devices Department of Mechanical and Aerospace Engineering Jacobs School of Engineering University of California San Diego La Jolla California USA.
Reiley WeekesMedically Advanced Devices Laboratory Center for Medical Devices Department of Mechanical and Aerospace Engineering Jacobs School of Engineering University of California San Diego La Jolla California USA.
William ConnacherMedically Advanced Devices Laboratory Center for Medical Devices Department of Mechanical and Aerospace Engineering Jacobs School of Engineering University of California San Diego La Jolla California USA.
Jeremy SiekerSchool of Medicine University of California San Diego La Jolla California USA.
Mark StambaughQualcomm Institute University of California San Diego La Jolla California USA.
Preetham SureshDepartment of Anaesthesiology School of Medicine University of California San Diego La Jolla California USA.
Daniel E LeeDepartment of Anaesthesiology School of Medicine University of California San Diego La Jolla California USA.
William MazzeiDepartment of Anaesthesiology School of Medicine University of California San Diego La Jolla California USA.
Eric SchlaepferIndependent Researcher Sunnyvale California USA.
Theodore VallejosDepartment of Respiratory Care School of Medicine University of California San Diego La Jolla California USA.
Johan PetersenDepartment of Anaesthesiology School of Medicine University of California San Diego La Jolla California USA.
Sidney MerrittDepartment of Anaesthesiology School of Medicine University of California San Diego La Jolla California USA.
Lonnie PetersenMedically Advanced Devices Laboratory Center for Medical Devices Department of Mechanical and Aerospace Engineering Jacobs School of Engineering University of California San Diego La Jolla California USA.
James FriendMedically Advanced Devices Laboratory Center for Medical Devices Department of Mechanical and Aerospace Engineering Jacobs School of Engineering University of California San Diego La Jolla California USA.
Acute Ventilation Rapid Response Taskforce (AVERT)
University of California, San Diego · USAdvanced Materials and Devices (United States) · USFilm Independent · USQualcomm (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has produced critical shortages of ventilators worldwide. There is an unmet need for rapidly deployable, emergency-use ventilators with sufficient functionality to manage COVID-19 patients with severe acute respiratory distress syndrome. Here, we show the development and validation of a simple, portable and low-cost ventilator that may be rapidly manufactured with minimal susceptibility to supply chain disruptions. This single-mode continuous, mandatory, closed-loop, pressure-controlled, time-terminated emergency ventilator offers robust safety and functionality absent in existing solutions to the ventilator shortage. Validated using certified test lungs over a wide range of compliances, pressures, volumes and resistances to meet U.S. Food and Drug Administration standards of safety and efficacy, an Emergency Use Authorization is in review for this system. This emergency ventilator could eliminate controversial ventilator rationing or splitting to serve multiple patients. All design and validation information is provided to facilitate ventilator production even in resource-limited settings.

Indexed as

acute respiratory distress syndromeCOVID‐19 pandemiccritical caremass casualty incidentsmechanical ventilationmedical device designrespiratory insufficiency

Identifiers

PMID32838208
PMCPMC7300530
OpenAlexW3034068641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.