Evidence map›Paper›PMID 32837915›Full record

ArticleInterdisciplinary neurosurgery : Advanced techniques and case management2020

Intracranial hemorrhage in a young COVID-19 patient.

Nicolas K Khattar, Mayur Sharma, Abigail P McCallum, Brent G Oxford, Hassan Zeb, Sally A Suliman, Emily P Sieg, J Mocco, Joseph S Neimat, Ajmal Zemmar

Open access · goldAbstract readCase Reports
In one paragraph

Article in Interdisciplinary neurosurgery : Advanced techniques and case management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Intracerebral hemorrhage in COVID-19: A narrative review.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2021
    Review
  7. Neurological manifestations and neuroimaging findings in patients with SARS-CoV2-a systematic review.The Egyptian journal of neurology, psychiatry and neurosurgery · 2021
    Review
  8. COVID-19-Related Intracerebral Hemorrhage.Frontiers in aging neuroscience · 2020
    Article
  9. COVID-19 and cerebrovascular diseases: a comprehensive overview.Therapeutic advances in neurological disorders · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Nicolas K KhattarDepartment of Neurosurgery, Henan Provincial People's Hospital, Henan University People's Hospital, Henan University School of Medicine, Zhengzhou, China.
Mayur SharmaDepartment of Neurological Surgery, University of Louisville School of Medicine, Louisville KY, USA.
Abigail P McCallumDepartment of Neurological Surgery, University of Louisville School of Medicine, Louisville KY, USA.
Brent G OxfordDepartment of Neurological Surgery, University of Louisville School of Medicine, Louisville KY, USA.
Hassan ZebDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY, USA.
Sally A SulimanDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY, USA.
Emily P SiegDepartment of Neurological Surgery, University of Louisville School of Medicine, Louisville KY, USA.
J MoccoDepartment of Neurological Surgery, Mount Sinai Medical Center, New York, NY USA.
Joseph S NeimatDepartment of Neurological Surgery, University of Louisville School of Medicine, Louisville KY, USA.
Ajmal ZemmarDepartment of Neurosurgery, Henan Provincial People's Hospital, Henan University People's Hospital, Henan University School of Medicine, Zhengzhou, China.
Neurological Surgery · USUniversity of Louisville · USHenan Provincial People's Hospital · CNHenan University · CNMount Sinai Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 patients are increasingly understood to develop multisystem manifestations, including neurologic involvement. We report the case of a 42-year old COVID-19 positive patient with a fatal intracerebral hemorrhage (ICH). The patient presented with fever and dyspnea, requiring intubation due to medical complications. After prolonged sedation and anticoagulation, the patient suddenly developed bilaterally fixed and dilated pupils, caused by a right-sided intracranial hemorrhage with uncal herniation. The course of this case illustrates the delicate balance between hypercoagulability and coagulation factor depletion; especially in the intubated and sedated patient, in whom regular neurological assessments are impeded. As we expand our understanding of the neurological ramifications of COVID-19, clinicians need to be increasingly aware of the precarious coagulation balance.

Indexed as

CoagulopathyCOVID-19InflammationIntracerebral hemorrhage

Identifiers

PMID32837915
PMCPMC7419270
OpenAlexW3048970920

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.