Evidence map›Paper›PMID 32837914›Full record

ArticleMeta gene2020

The Duffy T-33C is an insightful marker of human history and admixture.

Musab M Ali Albsheer, Ayman Hussien, Dominic Kwiatkowski, Muzamil Mahdi Abdel Hamid, Muntaser E Ibrahim

Abstract read
In one paragraph

Article in Meta gene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Musab M Ali AlbsheerInstitute of Endemic Diseases, University of Khartoum, Sudan.
Ayman HussienInstitute of Endemic Diseases, University of Khartoum, Sudan.
Dominic KwiatkowskiWeatherall's Institute of Molecular Medicine, University of Oxford, UK.
Muzamil Mahdi Abdel HamidInstitute of Endemic Diseases, University of Khartoum, Sudan.
Muntaser E IbrahimInstitute of Endemic Diseases, University of Khartoum, Sudan.

Funding

Medical Research Council MR/M006212/1Wellcome Trust 204911/Z/16/Z
6 · The paper itself

Abstract

A contrasting genotype and allele frequency pattern between Africans and non-Africans in the Duffy (T-33C) locus is reported. Its near fixation in various populations suggest is no longer under natural selection, and that current distribution is possibly a relic of distant extreme selection combined with genetic drift during the out of Africa. We put this difference into the utility to infer the ancestral state of ambiguous loci in different populations.

Identifiers

PMID32837914
PMCPMC7418637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.