Evidence map›Paper›PMID 32837898›Full record

ArticleAdvances in integrative medicine2020

The effects of

Janet Schloss, Matthew Leach, Danielle Brown, Nicole Hannan, Penny Kendall-Reed, Amie Steel

Open access · greenAbstract read
In one paragraph

Article in Advances in integrative medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. N-Acetylcysteine and Other Sulfur-Donors as a Preventative and Adjunct Therapy for COVID-19.Advances in pharmacological and pharmaceutical sciences · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Janet SchlossEndeavour College of Natural Health, Brisbane,Queensland, Australia.
Matthew LeachNational Centre for Naturopathic Medicine, Southern Cross University, Lismore, New South Wales, Australia.
Danielle BrownEndeavour College of Natural Health, Brisbane,Queensland, Australia.
Nicole HannanSchool of Pharmacy and Pharmacology, Griffith University, Gold Coast, Queensland, Australia.
Penny Kendall-ReedPKR Health, Toronto, Ontario, Canada.
Amie SteelAustralian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, New South Wales, Australia.
University of Technology Sydney · AUEndeavour College of Natural Health · AUGriffith University · AUSouthern Cross University · AUToronto Public Health · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current evidence suggests that N-Acetyl Cysteine (NAC) administration may help improve outcomes in people with acute respiratory distress syndrome and acute lung injury - conditions that closely resemble the signs and symptoms of COVID-19. Few mild and transient adverse events were reported in published randomised-controlled trials, indicating that NAC may be reasonably safe. These findings suggest that NAC may complement the management of COVID-19 infection, particularly when administered intravenously within an intensive care unit (ICU) environment.

Indexed as

Acute lung injuryCOVID-19NACN-acetyl cysteineRespiratory distress syndrome

Identifiers

PMID32837898
PMCPMC7398034
OpenAlexW3047156349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.