ReviewCurrent sleep medicine reports2020
Sleep and Delirium in Older Adults.
Review in Current sleep medicine reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05713877 (DELIRE-ICU), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
DELIRE-ICU: A Randomised Controlled Feasibility Trial of Melatonin vs Placebo in the Treatment of Delirium in the Intensive Care Unit
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Pooled it
- Incidence of adverse cardiovascular events in patients with insomnia: A systematic review and meta-analysis of real-world data.PloS one · 2023Pooled it
- Effectiveness of emotional freedom techniques (EFT) vs sleep hygiene education group therapy (SHE) in management of sleep disorders among elderly.Scientific reports · 2022Trial
- Application of Circadian Rhythm-Based Pulmonary Rehabilitation in Patients with Severe Pneumonia-A Feasibility Study With Convenience Sampling.Archives of rehabilitation research and clinical translation · 2026Article
- Reducing Excessive Continuous Pulse Oximetry and Promoting Patient Safety: An Electronic Health Record-Based Quality Improvement Effort.Journal of general internal medicine · 2026Article
- Glymphatic dysfunction: a unifying hypothesis for delirium.Nature reviews. Neurology · 2026Review
- Exploring bed sensor technology: interdisciplinary insights in a geriatric assessment inpatient setting.The Gerontologist · 2026Article
- Association between hypnotic medication use and in-hospital falls among older adults: A multicenter landmark analysis.PloS one · 2026Article
- Validation of the Richards-Campbell Sleep Questionnaire Against Actigraphy in Hospitalized Patients and Its Association with Delirium Risk.Nature and science of sleep · 2026Article
- There's No Place Like Home: Mitigating Delirium by Enhancing Sleep and Circadian Health in Home Hospital.Journal of general internal medicine · 2026Article
- Promoting Rehabilitation Using a Multimodal Internet of Things-Based Patient Monitoring System in a Smart Hospital.IEEE journal of translational engineering in health and medicine · 2026Article
- Optimizing Sleep Hygiene in the Hospital Environment.Sleep medicine clinics · 2025Review
- Prediction of out-of-hospital cardiac arrest in older patients with insomnia: a longitudinal population study.BMC geriatrics · 2025Article
- Promoting Sleep for Neurology Inpatients: The Value of Routine Overnight Vital Signs.Neurology. Clinical practice · 2025Article
- From Acute Confusion to Chronic Decline: The Cognitive Impact of Delirium in Older Adults.Rhode Island medical journal (2013) · 2025Review
- Article
- Construction and application of a stratified nursing intervention program for postoperative delirium after Stanford type A aortic dissection: a quasi-experimental trial.Perioperative medicine (London, England) · 2025Article
- Current perspectives on the early identification and management of delirium after acute stroke reperfusion therapy.Frontiers in neurology · 2025Review
- Article
- Development and Validation of Machine Learning Models to Predict Postoperative Delirium Using Clinical Features and Polysomnography Variables.Journal of clinical medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Purpose of Review: Poor sleep and delirium are common in older patients but recognition and management are challenging, particularly in the intensive care unit (ICU) setting. The purpose of this review is to highlight current research on these conditions, their inter-relationship, modes of measurement, and current approaches to management. Recent Findings: Sleep deprivation and delirium are closely linked, with shared clinical characteristics, risk factors, and neurochemical abnormalities. Acetylcholine and dopamine are important neurochemicals in the regulation of sleep and wakefulness and their dysregulation has been implicated in development of delirium. In the hospital setting, poor sleep and delirium are associated with adverse outcomes; non-pharmacological interventions are recommended, but tend to be resource intensive and hindered by a lack of reliable sleep measurement tools. Delirium is easier to identify, with validated tools available in both ICU and non-ICU settings; however, an optimal treatment approach remains unclear. Antipsychotics are used widely to prevent and treat delirium, although the efficacy data are equivocal. Bundled non-pharmacologic approaches represent a promising framework for prevention and management. Summary: Poor sleep and delirium are common problems in older patients. While these phenomena appear linked, a causal relationship is not clearly established. At present, there are no established sleep-focused guidelines for preventing or treating delirium. Novel interventions are needed that address poor sleep and delirium, particularly in older adults.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.