ReviewJournal of advanced research2020
Molecular diagnostic technologies for COVID-19: Limitations and challenges.
Review in Journal of advanced research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 176 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
176 citing papers in PubMed, 2 syntheses or guidelines pooled it, 379 citations in OpenAlex.
- Diagnostic Accuracy of Rapid Antigen Tests for COVID-19 Detection: A Systematic Review With Meta-analysis.Frontiers in medicine · 2022Pooled it
- The NICE COVID-19 rapid guideline on haematopoietic stem cell transplantation: development, implementation and impact.British journal of haematology · 2021Guideline
- A field deployable duplex RPA-CRISPR/Cas12a assay for rapid and sensitive detection of African swine fever virus.Archives of virology · 2026Article
- Droplet digital PCR-based nucleic acid amplification test for improved molecular and clinical diagnosis of severe fever with thrombocytopenia syndrome patients.Journal of clinical microbiology · 2026Article
- Surface-Enhanced Raman Spectroscopy for Viral Diagnostics: Principles, Strategies, Clinical Challenges, and Future Directions.Chemical reviews · 2026Review
- Diagnostic Performance Evaluation of the GXT96 X3 Extraction System with the FluoroTypeDiagnostics (Basel, Switzerland) · 2026Article
- High exposure of pregnant women to SARS-CoV-2 during COVID-19 waves in Senegal.BMC pregnancy and childbirth · 2026Article
- A knowledge-guided deep learning framework for quantitative nucleic acid testing.Briefings in bioinformatics · 2026Article
- Perspectives from Sri Lankan physicians on current approaches to diagnosing and managing lower respiratory tract infections.BMC research notes · 2026Article
- Enhanced SfaTnpB enables single-base-specific, one-pot nucleic acid detection for high-sensitivity diagnostics.Nucleic acids research · 2026Article
- Development of RT-LAMP assay for variants of HCV in Pakistan.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Sleep Disturbance and Chronic Urticaria: A Narrative Review of Its Relationship, Treatment and Evolving Literature.Health science reports · 2025Article
- Long Term Impact of Adeno-tonsillectomy on Immunity Against Respiratory Viral Infections; Evidence Deduced During COVID-19 Pandemic.Indian journal of pediatrics · 2025Article
- Block copolymer-assembled nanopore arrays enable ultrasensitive label-free DNA detection.Nanoscale horizons · 2025Article
- Lab-on-paper for molecular testing with USB-powered isothermal amplification and fluidic control.Mikrochimica acta · 2025Article
- Fast and Sensitive Detection of Anti-SARS-CoV-2 IgG Using SiOBiomolecules · 2024Article
- Comparison of a Commercial SARS-CoV-2 Rapid Antigen Test with Real-Time PCR.Infectious diseases & clinical microbiology · 2024Article
- Development of a High-Resolution Melting Method for the Detection of Clarithromycin-ResistantAntibiotics (Basel, Switzerland) · 2024Article
- From Species to Genes: A New Diagnostic Paradigm.Antibiotics (Basel, Switzerland) · 2024Review
- Strategies for Increasing the Throughput of Genetic Screening: Lessons Learned from the COVID-19 Pandemic within a University Community.Biotech (Basel (Switzerland)) · 2024Article
116 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo curb the spread of the COVID-19 (coronavirus disease 2019) pandemic, the world needs diagnostic systems capable of rapid detection and quantification of the novel coronavirus (SARS-CoV-2). Many biomedical companies are rising to the challenge and developing COVID-19 diagnostics. In the last few months, some of these diagnostics have become commercially available for healthcare workers and clinical laboratories. However, the diagnostic technologies have specific limitations and reported several false-positive and false-negative cases, especially during the early stages of infection.
aimThis article aims to review recent developments in the field of COVID-19 diagnostics based on molecular technologies and analyze their clinical performance data. KEY CONCEPTS: The literature survey and performance-based analysis of the commercial and pre-commercial molecular diagnostics address several questions and issues related to the limitations of current technologies and highlight future research and development challenges to enable timely, rapid, low-cost, and accurate diagnosis of emerging infectious diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.