Evidence map›Paper›PMID 32837093›Full record

ReviewJournal of clinical and experimental hepatology

COVID-19 Vaccines: A Race Against Time in the Middle of Death and Devastation!

Mohammad S Khuroo, Mohammad Khuroo, Mehnaaz S Khuroo, Ahmad A Sofi, Naira S Khuroo

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. A risk science perspective on vaccines.Risk analysis : an official publication of the Society for Risk Analysis · 2024
    Article
  4. Article
  5. COVID-19 vaccines: current and future challenges.Frontiers in pharmacology · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Risk Perception and Acceptability of the COVID-19 Vaccine in Nigeria.Turkish journal of pharmaceutical sciences · 2022
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Cross-species virus transmission and its pandemic potential.Bulletin of the National Research Centre · 2022
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mohammad S KhurooMedicine, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir, India.
Mohammad KhurooIndian School Al-Ghubrah, Muscat, Oman.
Mehnaaz S KhurooPathology, Government Medical College, Srinagar, Kashmir, J&K (UT), 190010, India.
Ahmad A SofiBurn Hall School, Srinagar, J&K (UT), 190010, India.
Naira S KhurooGastroenterology and Liver Transplantation, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Government Medical College · INKing Faisal Specialist Hospital & Research Centre · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) has turned into a global human tragedy and economic devastation. Governments have implemented lockdown measures, blocked international travel, and enforced other public containment measures to mitigate the virus morbidity and mortality. As of today, no drug has the power to fight the infection and bring normalcy to the utter chaos. This leaves us with only one choice namely an effective and safe vaccine that shall be manufactured as soon as possible and available to all countries and populations affected by the pandemic at an affordable price. There has been an unprecedented fast track path taken in Research & Development by the World community for developing an effective and safe vaccine. Platform technology has been exploited to develop candidate vaccines in a matter of days to weeks, and as of now, 108 such vaccines are available. Six of these vaccines have entered clinical trials. As clinical trials are "rate-limiting" and "time-consuming", many innovative methods are in practice for a fast track. These include parallel phase I-II trials and obtaining efficacy data from phase IIb trials. Human "challenge experiments" to confirm efficacy in humans is under serious consideration. The availability of the COVID-19 vaccine has become a race against time in the middle of death and devastation. There is an atmosphere of tremendous hype around the COVID-19 vaccine, and developers are using every moment to make claims, which remain unverified. However, concerns are raised about a rush to deploy a COVID-19 vaccine. Applying "Quick fix" and "short cuts" can lead to errors with disastrous consequences.

Indexed as

ADE, Antibody-Dependent EnhancementCEPI, Coalition for Epidemic Preparedness InnovationscoronavirusCOVID-19COVID-19, Coronavirus Disease 2019MERS-CoV, Middle East Respiratory Syndrome CoronavirusMHC, Major Histocompatibility Complexplatform technology clinical trialsSARS-CoV-2SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2vaccineWHO, World Health Organization

Identifiers

PMID32837093
PMCPMC7286271
OpenAlexW3025872080

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.