ArticleDevelopmental cognitive neuroscience2020
Influences of affective context on amygdala functional connectivity during cognitive control from adolescence through adulthood.
Article in Developmental cognitive neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed.
- Neuroimaging and Emotional Development in the Pediatric Population: Understanding the Link Between the Brain, Emotions, and Behavior.Pediatric reports · 2025Review
- Sleep problems, decision-making, and suicide attempts during adolescence: a longitudinal birth cohort study.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Age-related differences in affective behaviors in mice: possible role of prefrontal cortical-hippocampal functional connectivity and metabolomic profiles.Frontiers in aging neuroscience · 2024Article
- Immature excitatory neurons in the amygdala come of age during puberty.Developmental cognitive neuroscience · 2022Article
- Neurobehavioral maturation of motor response inhibition in adolescence - A narrative review.Neuroscience and biobehavioral reviews · 2022Review
- Day-to-Day Decision Making by Adolescents and Young Adults with Cancer.Journal of pediatric hematology/oncology nursingArticle
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Authors and funding
7 authors.
Funding
Abstract
Emotion processing is believed to dominate over other brain functions during adolescence, including inhibitory control. However, few studies have examined the neural underpinnings of affective states during cognitive control. Here, we characterized the brain in an affective state by cross-sectionally assessing age-related changes in amygdala background connectivity during an affective inhibitory control task. Participants completed an antisaccade (AS) fMRI task while affective auditory stimuli were presented, and a 5-minute resting state scan. Results showed that while adolescents reported similar arousal levels across emotional conditions, adults perceived negative sounds to be more "arousing" and performed better than adolescents in negative trials. Amygdala background connectivity showed age-related increases with brain regions related to attention and executive control, which were not evident during resting state. Together, results suggest that amygdala connectivity within an affective context is fairly low in mid-adolescence but much stronger in adulthood, supporting age-related improvements in inhibitory control within an affective state. These findings suggest limitations during adolescence in differentiating between the arousing effects of various emotions, potentially undermining the ability to optimally engage inhibitory control. Furthermore, the age-related fMRI findings suggest that low amygdala connectivity to brain areas involved in executive control may underlie these limited abilities during adolescence.
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