Evidence map›Paper›PMID 32835899›Full record

ArticleSleep medicine2020

Prediction of sleep-disordered breathing after stroke.

Devin L Brown, Kevin He, Sehee Kim, Chia-Wei Hsu, Erin Case, Ronald D Chervin, Lynda D Lisabeth

Open access · greenAbstract read
In one paragraph

Article in Sleep medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Racial and ethnic differences in sleep-disordered breathing and sleep duration among stroke patients.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
  8. Review
  9. Diagnosis of Obstructive Sleep Apnea in Patients with Associated Comorbidity.Advances in experimental medicine and biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Devin L BrownStroke Program, University of Michigan, United States. Electronic address: devinb@umich.edu.
Kevin HeDepartment of Biostatistics, School of Public Health, University of Michigan, United States.
Sehee KimDepartment of Biostatistics, School of Public Health, University of Michigan, United States.
Chia-Wei HsuDepartment of Epidemiology, School of Public Health, University of Michigan, United States.
Erin CaseStroke Program, University of Michigan, United States; Department of Epidemiology, School of Public Health, University of Michigan, United States.
Ronald D ChervinSleep Disorders Center and Department of Neurology, University of Michigan, United States.
Lynda D LisabethStroke Program, University of Michigan, United States; Department of Epidemiology, School of Public Health, University of Michigan, United States.
University of Michigan–Ann Arbor · USMichigan United · US

Funding

Childhood Liver Disease Research Network Data Coordinating CenterU01DK062456 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MAGEE, JOHN C, MERION, ROBERT M · 2002 to 2019
$36.8M
Sleep for Stroke Management And Recovery Trial (Sleep SMART)U01NS099043 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DEVIN L BROWN, RONALD D CHERVIN · 2018 to 2026
$31.7M
STROKE SURVEILLANCE IN A BIETHNIC COMMUNITYR01NS038916 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LISABETH, LYNDA D, MORGENSTERN, LEWIS B · 1999 to 2023
$20.9M
IMPACT OF TREATMENT OF MILD SLEEP-DISORDERED BREATHING ON CHILDREN'S HEALTH-CCCU01HL125295 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI FURTH, SUSAN L. · 2015 to 2019
$7.9M
Multi-Institutional Training in Genetic/Genomic Approaches to Sleep DisordersT32HL110952 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHERVIN, RONALD D, MIGNOT, EMMANUEL J · 2013 to 2022
$5.0M
Survival Analysis Methods for Organ Failure DataR01DK070869 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI DOUGLAS EARL SCHAUBEL · 2005 to 2026
$4.7M
Improving Post-Acute Care to Reduce Ethnic Stroke DisparitiesR01NS107463 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LISABETH, LYNDA D, MORGENSTERN, LEWIS B · 2019 to 2023
$3.3M
Sleep-Disordered Breathing and CPAP after Adenotonsillectomy in ChildrenR01HL105999 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHERVIN, RONALD D · 2012 to 2016
$3.2M
Sleep apnea after stroke: Implications for screening and treatmentR01HL126700 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROWN, DEVIN L, LISABETH, LYNDA D · 2016 to 2019
$3.0M
Increasing Sleep Health Literacy in Head Start: A Social-Ecological ApproachR01HD082129 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BONUCK, KAREN A. · 2015 to 2019
$2.9M
Outcomes Among Surrogate decision makers In Stroke (OASIS)R01NS091112 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORGENSTERN, LEWIS B, ZAHURANEC, DARIN B · 2015 to 2019
$2.6M
Sleep apnea health disparities in Mexican American stroke patientsR01NS070941 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROWN, DEVIN L, LISABETH, LYNDA D · 2011 to 2015
$2.6M
NHLBI NIH HHS R01 HL098065NHLBI NIH HHS R01 HL105999NHLBI NIH HHS R01 HL123379NHLBI NIH HHS R01 HL126700NHLBI NIH HHS R43 HL117421NHLBI NIH HHS T32 HL110952NHLBI NIH HHS U01 HL125295NIA NIH HHS R21 AG060277NICHD NIH HHS R01 HD082129NIDDK NIH HHS R01 DK070869NIDDK NIH HHS U01 DK062456NINDS NIH HHS R01 NS038916NINDS NIH HHS R01 NS070941NINDS NIH HHS R01 NS091112NINDS NIH HHS R01 NS107463NINDS NIH HHS U01 NS099043
6 · The paper itself

Abstract

OBJECTIVE/

backgroundSleep-disordered breathing (SDB) is highly prevalent after stroke and is associated with poor outcomes. Currently, after stroke, objective testing must be used to differentiate patients with and without SDB. Within a large, population-based study, we evaluated the usefulness of a flexible statistical model based on baseline characteristics to predict post-stroke SDB. PATIENTS/

methodsWithin a population-based study, participants (2010-2018) underwent SDB screening, shortly after ischemic stroke, with a home sleep apnea test. The respiratory event index (REI) was calculated as the number of apneas and hypopneas per hour of recording; values ≥10 defined SDB. The distributed random forest classifier (a machine learning technique) was applied to predict SDB with the following as predictors: demographics, stroke risk factors, stroke severity (NIHSS), neck and waist circumference, palate position, and pre-stroke symptoms of snoring, apneas, and sleepiness.

resultsWithin the total sample (n = 1330), median age was 65 years; 47% were women; 32% non-Hispanic white, 62% Mexican American, and 6% African American. SDB was found in 891 (67%). The area under the receiver operating characteristic curve, a measure of predictive ability, applied to the validation sample was 0.75 for the random forest model. Random forest correctly classified 72.5% of validation samples.

conclusionsIn this large, ethnically diverse, population-based sample of ischemic stroke patients, prediction models based on baseline characteristics and clinical measures showed fair rather than clinically reliable performance, even with use of advanced machine learning techniques. Results suggest that objective tests are still needed to differentiate ischemic stroke patients with and without SDB.

Indexed as

Sleep Apnea SyndromesStrokeAgedFemaleHumansMalePolysomnographyRisk FactorsSnoringSleep apneaSleep-disordered breathingStroke

Identifiers

PMID32835899
PMCPMC7666648
OpenAlexW3024993901

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.