ArticleJournal of molecular and cellular cardiology2020
Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19.
Article in Journal of molecular and cellular cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Cardiac Magnetic Resonance Imaging of COVID-19-Associated Cardiac Sequelae: A Systematic Review.Reviews in cardiovascular medicine · 2022Pooled it
- Mortality and risk factors associated with pulmonary embolism in coronavirus disease 2019 patients: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- Potential Mechanisms of COVID-19 Related Nervous System Damage and Effects on Female Fertility.Current medicinal chemistry · 2025Review
- The impact of sex/gender-specific funding and editorial policies on biomedical research outcomes: a cross-national analysis (2000-2021).Scientific reports · 2024Article
- Ocular and systemic determinants of perifoveal and macular vessel parameters in healthy African Americans.The British journal of ophthalmology · 2023Article
- Article
- COVID-19's immuno-pathology and cardiovascular diseases.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2023Review
- [Study analysis evaluating the management and epidemiological aspects of the COVID-19 pandemic in Senegal one year on].The Pan African medical journal · 2023Article
- Sex differences in cardiovascular complications and mortality in hospital patients with covid-19: registry based observational study.BMJ medicine · 2023Article
- Cardiometabolic Risk after SARS-CoV-2 Virus Infection: A Retrospective Exploratory Analysis.Journal of personalized medicine · 2022Article
- The sex and gender dimensions of COVID-19: A narrative review of the potential underlying factors.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2022Review
- A close-up view of dynamic biomarkers in the setting of COVID-19: Striking focus on cardiovascular system.Journal of cellular and molecular medicine · 2022Review
- Depression pandemic and cardiovascular risk in the COVID-19 era and long COVID syndrome: Gender makes a difference.Trends in cardiovascular medicine · 2022Review
- The Potential Impact of COVID-19 Virus on the Heart and the Circulatory System.Infection and drug resistance · 2022Review
- Biomarkers of Cardiac Injury, Renal Injury, and Inflammation Are Strong Mediators of Sex-Associated Death in COVID-19.Frontiers in cardiovascular medicine · 2022Article
- Roles of steroid receptors in the lung and COVID-19.Essays in biochemistry · 2021Review
- Article
- The hidden interplay between sex and COVID-19 mortality: the role of cardiovascular calcification.GeroScience · 2021Article
- Sex- or Gender-specific Differences in the Clinical Presentation, Outcome, and Treatment of SARS-CoV-2.Clinical therapeutics · 2021Review
- The Female Athlete's Heart: Overview and Management of Cardiovascular Diseases.European cardiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
The novel 2019 coronavirus disease (COVID-19), resulting from severe acute respiratory syndrome coronarvirus-2 (SARS-CoV-2) infection, typically leads to respiratory failure in severe cases; however, cardiovascular injury is reported to contribute to a substantial proportion of COVID-19 deaths. Preexisting cardiovascular disease (CVD) is among the most common risk factors for hospitalization and death in COVID-19 patients, and the pathogenic mechanisms of COVID-19 disease progression itself may promote the development of cardiovascular injury, increasing risk of in-hospital death. Sex differences in COVID-19 are becoming more apparent as mounting data indicate that males seem to be disproportionately at risk of severe COVID-19 outcome due to preexisting CVD and COVID-19-related cardiovascular injury. In this review, we will provide a basic science perspective on current clinical observations in this rapidly evolving field and discuss the interplay sex differences, preexisting CVD and COVID-19-related cardiac injury.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.