Evidence map›Paper›PMID 32835479›Full record

ArticleACS chemical biology2020

Sequential Linkage of Carbohydrate Antigens to Mimic Capsular Polysaccharides: Toward Semisynthetic Glycoconjugate Vaccine Candidates against

Bruna M S Seco, Fei-Fei Xu, Andrea Grafmüller, Naresh Kottari, Claney L Pereira, Peter H Seeberger

Open access · hybridAbstract read
In one paragraph

Article in ACS chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Synthetic Access to Fluorinated Analogs of a KnownACS organic & inorganic Au · 2026
    Article
  3. Review
  4. Review
  5. Semi-Synthetic Glycoconjugate Vaccine Lead Against Acinetobacter baumannii 17978.Angewandte Chemie (International ed. in English) · 2022
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bruna M S SecoDepartment of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.
Fei-Fei XuDepartment of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.
Andrea GrafmüllerDepartment of Theory and Bio-Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.ORCID 0000-0002-1671-3158
Naresh KottariDepartment of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.
Claney L PereiraDepartment of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.
Peter H SeebergerDepartment of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.ORCID 0000-0003-3394-8466
Max Planck Institute of Colloids and Interfaces · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines based on isolated polysaccharides successfully protect humans from bacterial pathogens such as

Indexed as

AnimalsCarbohydrate SequenceCarrier ProteinsEpitopesFemaleGlycoconjugatesHL-60 CellsHumansMice, Inbred C57BLMolecular Dynamics SimulationOligosaccharidesSerogroupStreptococcal VaccinesStreptococcus pneumoniaeVaccines, ConjugateCarrier ProteinsEpitopesGlycoconjugatesOligosaccharidesStreptococcal VaccinesVaccines, Conjugate

Identifiers

PMID32835479
PMCPMC7506939
OpenAlexW3080923603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.